Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0018 | 0 | 0.5 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0021 | 0.028 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0018 | 0 | 0.5 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0021 | 0.028 | 0.5 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0018 | 0 | 0.5 |
Brugia malayi | Kringle domain containing protein | 0.0018 | 0 | 0.5 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0088 | 0.8361 | 0.5 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0021 | 0.028 | 0.5 |
Mycobacterium leprae | TWO COMPONENT SENSOR HISTIDINE KINASE PRRB | 0.0088 | 0.8361 | 0.5 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0021 | 0.028 | 0.5 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0018 | 0 | 0.5 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0088 | 0.8361 | 0.5 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0018 | 0 | 0.5 |
Toxoplasma gondii | kringle domain-containing protein | 0.0018 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0021 | 0.028 | 0.5 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0088 | 0.8361 | 0.5 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0021 | 0.028 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0018 | 0 | 0.5 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0021 | 0.028 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0 | 0.5 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0021 | 0.028 | 0.5 |
Onchocerca volvulus | 0.0018 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.