Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phospholipase D2 | Starlite/ChEMBL | References |
Homo sapiens | phospholipase D1, phosphatidylcholine-specific | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.0043 | 0.1973 | 0.5 |
Leishmania major | phosphatidylglycerophosphate synthase, putative | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.5702 | 0.7103 |
Trypanosoma brucei | cardiolipin synthetase | 0.0043 | 0.1973 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.8027 | 1 |
Brugia malayi | Phospholipase D. Active site motif family protein | 0.0043 | 0.1973 | 0.1973 |
Echinococcus multilocularis | phospholipase D | 0.011 | 0.8562 | 0.8562 |
Entamoeba histolytica | phospholipase D, putative | 0.0124 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.8027 | 1 |
Echinococcus granulosus | phospholipase D1 | 0.0124 | 1 | 1 |
Schistosoma mansoni | phospholipase D | 0.0124 | 1 | 0.5 |
Entamoeba histolytica | phospholipase D, putative | 0.0124 | 1 | 1 |
Trypanosoma brucei | cardiolipin synthetase, putative | 0.0043 | 0.1973 | 0.5 |
Onchocerca volvulus | Putative phospholipase D | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.5702 | 0.7103 |
Toxoplasma gondii | phospholipase D active site domain-containing protein | 0.0043 | 0.1973 | 0.5 |
Echinococcus granulosus | phospholipase D | 0.011 | 0.8562 | 0.8562 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.0043 | 0.1973 | 0.5 |
Echinococcus multilocularis | phospholipase D1 | 0.0124 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.