Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | nitroreductase | 0.0055 | 0 | 0.5 |
Brugia malayi | nitroreductase family protein | 0.0055 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0 | 0.5 |
Entamoeba histolytica | nitroreductase family protein | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Giardia lamblia | Nitroreductase family protein fused to ferredoxin domain Fd-NR1 | 0.0055 | 0 | 0.5 |
Entamoeba histolytica | nitroreductase family protein | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0055 | 0 | 0.5 |
Onchocerca volvulus | Iodotyrosine dehalogenase 1 homolog | 0.0055 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | nitroreductase | 0.0055 | 0 | 0.5 |
Entamoeba histolytica | nitroreductase family protein | 0.0055 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Mycobacterium leprae | Possible oxidoreductase | 0.0055 | 0 | 0.5 |
Mycobacterium leprae | Probable F420 biosynthesis protein FbiB | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | nitroreductase | 0.0055 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable F420 biosynthesis protein FbiB | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trypanosoma cruzi | nitroreductase | 0.0629 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trypanosoma brucei | nitroreductase | 0.0629 | 1 | 1 |
Giardia lamblia | Nitroreductase family protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Mycobacterium tuberculosis | Putative oxidoreductase | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | nitroreductase | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein Acg | 0.0055 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trypanosoma cruzi | nitroreductase | 0.0629 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0055 | 0 | 0.5 |
Mycobacterium ulcerans | F420-0--gamma-glutamyl ligase | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0 | 0.5 |
Giardia lamblia | Nitroreductase Fd-NR2 | 0.0055 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.