Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glucose transport protein | 0.0323 | 0.2561 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.01 | 0 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.01 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0323 | 0.2561 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter | 0.01 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.01 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0323 | 0.2561 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Plasmodium falciparum | hexose transporter | 0.0323 | 0.2561 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0323 | 0.2561 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Leishmania major | glucose transporter, lmgt3 | 0.01 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.01 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.01 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Leishmania major | glucose transporter, lmgt1 | 0.01 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0323 | 0.2561 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0323 | 0.2561 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt2 | 0.01 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0969 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0323 | 0.2561 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.01 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Brugia malayi | Sugar transporter family protein | 0.0323 | 0.2561 | 0.5 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0323 | 0.2561 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.01 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Trypanosoma brucei | glucose transporter 2A | 0.01 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0323 | 0.2561 | 1 |
Trypanosoma brucei | glucose transporter 1E | 0.01 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.01 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.