Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.3651 | 0.4062 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.009 | 0.3646 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.011 | 0.5626 | 0.5626 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0143 | 0.8988 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0063 | 0.1012 | 0.1012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.009 | 0.3646 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0063 | 0.1012 | 0.1012 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.009 | 0.3646 | 0.5 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0143 | 0.8988 | 0.5 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0063 | 0.1012 | 0.1012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0063 | 0.1012 | 0.1012 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0134 | 0.8025 | 0.8025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0153 | 1 | 1 |
Echinococcus granulosus | glutamate receptor 1 | 0.009 | 0.3651 | 0.3651 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.009 | 0.3646 | 0.5 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.011 | 0.5626 | 0.5626 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.3651 | 0.4062 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0153 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0143 | 0.8988 | 0.5 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0063 | 0.1012 | 0.1012 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.009 | 0.3646 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0134 | 0.8025 | 0.8025 |
Echinococcus granulosus | glutamate receptor 4 | 0.009 | 0.3651 | 0.3651 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0063 | 0.1012 | 0.1012 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0063 | 0.1012 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0143 | 0.8988 | 0.8988 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.009 | 0.3646 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.3651 | 0.4062 |
Echinococcus multilocularis | glutamate receptor 4 | 0.009 | 0.3651 | 0.3651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.3646 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 128 ug ml-1 | Antibacterial activity against Escherichia coli K-12 after 24 hrs by microdilution method | ChEMBL. | 21534606 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.