Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phosphorylase, glycogen, liver | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.4248 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.4248 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.4248 | 1 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0496 | 0.0496 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.013 | 0.4248 | 1 |
Onchocerca volvulus | 0.0033 | 0.0496 | 0.1167 | |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.4248 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0496 | 0.0496 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.4248 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0496 | 0.0496 |
Loa Loa (eye worm) | plexin A | 0.0024 | 0.0144 | 0.0144 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.4248 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.013 | 0.4248 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0496 | 0.1167 |
Schistosoma mansoni | glycogen phosphorylase | 0.0056 | 0.1391 | 0.3274 |
Brugia malayi | plexin A | 0.0024 | 0.0144 | 0.0144 |
Echinococcus granulosus | MAM | 0.0033 | 0.0496 | 0.0857 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0496 | 0.0496 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.4248 | 1 |
Echinococcus multilocularis | MAM | 0.0033 | 0.0496 | 0.0857 |
Brugia malayi | carbohydrate phosphorylase | 0.013 | 0.4248 | 0.4248 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0056 | 0.1391 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.8629 | 0.8632 |
Onchocerca volvulus | 0.0033 | 0.0496 | 0.1167 | |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0279 | 0.9996 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.013 | 0.4248 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.4248 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.4248 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.013 | 0.4248 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.013 | 0.4248 | 0.425 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0056 | 0.1391 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.013 | 0.4248 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0496 | 0.1167 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.4248 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 1.2 uM | Inhibition of human liver glycogen phosphorylase a | ChEMBL. | 18434170 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.