Detailed view for Smp_101170

Basic information

TDR Targets ID: 283747
Schistosoma mansoni, hypothetical protein
Source Database / ID:  GeneDB

pI: 10.5625 | Length (AA): 107 | MW (Da): 11617 | Paralog Number: 118

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

No Pfam domain information for this protein.

Gene Ontology

Mouse over links to read term descriptions.
No GO information for this protein.

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There is 1 model calculated for this protein. More info on this model, including the model itself is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
5 101 2k8p (A) 29 108 39.00 0.65 0.05 0.696242 2.35

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_127305)

Species Accession Gene Product
Schistosoma japonicum Sjp_0119810   expressed protein
Schistosoma japonicum Sjp_0125380   expressed protein
Schistosoma japonicum Sjp_0130360   expressed protein
Schistosoma japonicum Sjp_0125630   expressed protein
Schistosoma japonicum Sjp_0219500   expressed protein
Schistosoma mansoni Smp_111330   hypothetical protein
Schistosoma mansoni Smp_184830   hypothetical protein
Schistosoma mansoni Smp_100680   hypothetical protein
Schistosoma mansoni Smp_113150   hypothetical protein
Schistosoma mansoni Smp_107730   hypothetical protein
Schistosoma mansoni Smp_110010   hypothetical protein
Schistosoma mansoni Smp_109170   hypothetical protein
Schistosoma mansoni Smp_111920   hypothetical protein
Schistosoma mansoni Smp_112400   hypothetical protein
Schistosoma mansoni Smp_110240   hypothetical protein
Schistosoma mansoni Smp_112430   hypothetical protein
Schistosoma mansoni Smp_073820   hypothetical protein
Schistosoma mansoni Smp_100740   hypothetical protein
Schistosoma mansoni Smp_110900   hypothetical protein
Schistosoma mansoni Smp_109760   hypothetical protein
Schistosoma mansoni Smp_107560   hypothetical protein
Schistosoma mansoni Smp_112670   hypothetical protein
Schistosoma mansoni Smp_116960   hypothetical protein
Schistosoma mansoni Smp_110260   hypothetical protein
Schistosoma mansoni Smp_109070   hypothetical protein
Schistosoma mansoni Smp_117290   hypothetical protein
Schistosoma mansoni Smp_111820   hypothetical protein
Schistosoma mansoni Smp_101190   hypothetical protein
Schistosoma mansoni Smp_110670   hypothetical protein
Schistosoma mansoni Smp_111080   hypothetical protein
Schistosoma mansoni Smp_106220   hypothetical protein
Schistosoma mansoni Smp_109200   hypothetical protein
Schistosoma mansoni Smp_100590   hypothetical protein
Schistosoma mansoni Smp_111680   hypothetical protein
Schistosoma mansoni Smp_111210   hypothetical protein
Schistosoma mansoni Smp_113120   hypothetical protein
Schistosoma mansoni Smp_111790   hypothetical protein
Schistosoma mansoni Smp_108750   hypothetical protein
Schistosoma mansoni Smp_107150   hypothetical protein
Schistosoma mansoni Smp_118330   hypothetical protein
Schistosoma mansoni Smp_072260   hypothetical protein
Schistosoma mansoni Smp_109380   hypothetical protein
Schistosoma mansoni Smp_112790   hypothetical protein
Schistosoma mansoni Smp_109400   hypothetical protein
Schistosoma mansoni Smp_111480   hypothetical protein
Schistosoma mansoni Smp_112440   hypothetical protein
Schistosoma mansoni Smp_109350   hypothetical protein
Schistosoma mansoni Smp_113450   hypothetical protein
Schistosoma mansoni Smp_107750   hypothetical protein
Schistosoma mansoni Smp_107160   hypothetical protein
Schistosoma mansoni Smp_111250   hypothetical protein
Schistosoma mansoni Smp_109970   hypothetical protein
Schistosoma mansoni Smp_112290   hypothetical protein
Schistosoma mansoni Smp_107610   hypothetical protein
Schistosoma mansoni Smp_117850   hypothetical protein
Schistosoma mansoni Smp_108010   hypothetical protein
Schistosoma mansoni Smp_112770   hypothetical protein
Schistosoma mansoni Smp_101170   hypothetical protein
Schistosoma mansoni Smp_110620   hypothetical protein
Schistosoma mansoni Smp_185650   hypothetical protein
Schistosoma mansoni Smp_110700   hypothetical protein
Schistosoma mansoni Smp_110530   hypothetical protein
Schistosoma mansoni Smp_111550   hypothetical protein
Schistosoma mansoni Smp_110460   hypothetical protein
Schistosoma mansoni Smp_112070   hypothetical protein
Schistosoma mansoni Smp_112730   hypothetical protein
Schistosoma mansoni Smp_112580   hypothetical protein
Schistosoma mansoni Smp_101010   hypothetical protein
Schistosoma mansoni Smp_107030   hypothetical protein
Schistosoma mansoni Smp_108800   hypothetical protein
Schistosoma mansoni Smp_112720   hypothetical protein
Schistosoma mansoni Smp_100550   hypothetical protein
Schistosoma mansoni Smp_110290   hypothetical protein
Schistosoma mansoni Smp_110220   hypothetical protein
Schistosoma mansoni Smp_101020   hypothetical protein
Schistosoma mansoni Smp_109270   hypothetical protein
Schistosoma mansoni Smp_109780   hypothetical protein
Schistosoma mansoni Smp_178020   hypothetical protein
Schistosoma mansoni Smp_107500   hypothetical protein
Schistosoma mansoni Smp_111700   hypothetical protein
Schistosoma mansoni Smp_111770   hypothetical protein
Schistosoma mansoni Smp_109490   hypothetical protein
Schistosoma mansoni Smp_100450   hypothetical protein
Schistosoma mansoni Smp_111060   hypothetical protein
Schistosoma mansoni Smp_113250   hypothetical protein
Schistosoma mansoni Smp_182320   hypothetical protein
Schistosoma mansoni Smp_113080   hypothetical protein
Schistosoma mansoni Smp_112160   hypothetical protein
Schistosoma mansoni Smp_111810   hypothetical protein
Schistosoma mansoni Smp_178160   hypothetical protein
Schistosoma mansoni Smp_109910   hypothetical protein
Schistosoma mansoni Smp_110130   hypothetical protein
Schistosoma mansoni Smp_109160   hypothetical protein
Schistosoma mansoni Smp_115760   hypothetical protein
Schistosoma mansoni Smp_109150   hypothetical protein
Schistosoma mansoni Smp_108690   hypothetical protein
Schistosoma mansoni Smp_106240   hypothetical protein
Schistosoma mansoni Smp_107600   hypothetical protein
Schistosoma mansoni Smp_110120   hypothetical protein
Schistosoma mansoni Smp_117860   hypothetical protein
Schistosoma mansoni Smp_108860   hypothetical protein
Schistosoma mansoni Smp_108740   hypothetical protein
Schistosoma mansoni Smp_115920   hypothetical protein
Schistosoma mansoni Smp_109790   hypothetical protein
Schistosoma mansoni Smp_117250   hypothetical protein
Schistosoma mansoni Smp_110140   hypothetical protein
Schistosoma mansoni Smp_110170   hypothetical protein
Schistosoma mansoni Smp_185290   hypothetical protein
Schistosoma mansoni Smp_112320   hypothetical protein
Schistosoma mansoni Smp_110600   hypothetical protein
Schistosoma mansoni Smp_185330   hypothetical protein
Schistosoma mansoni Smp_112340   hypothetical protein
Schistosoma mansoni Smp_110150   hypothetical protein
Schistosoma mansoni Smp_110540   hypothetical protein
Schistosoma mansoni Smp_110300   hypothetical protein
Schistosoma mansoni Smp_183920   hypothetical protein
Schistosoma mansoni Smp_111170   hypothetical protein
Schistosoma mansoni Smp_109470   hypothetical protein
Schistosoma mansoni Smp_100400   hypothetical protein
Schistosoma mansoni Smp_109890   hypothetical protein
Schistosoma mansoni Smp_095400   hypothetical protein
Schistosoma mansoni Smp_106460   hypothetical protein
Schistosoma mansoni Smp_109290   hypothetical protein
Schistosoma mansoni Smp_108770   hypothetical protein

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier Smp_101170 (Schistosoma mansoni), hypothetical protein
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