Detailed view for Smp_172120

Basic information

TDR Targets ID: 295840
Schistosoma mansoni, hypothetical protein
Source Database / ID:  GeneDB

pI: 6.601 | Length (AA): 314 | MW (Da): 36290 | Paralog Number: 0

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF10561   Uncharacterised protein family UPF0565

Gene Ontology

Mouse over links to read term descriptions.
No GO information for this protein.

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_133245)

Species Accession Gene Product
Drosophila melanogaster Dmel_CG31122   CG31122 gene product from transcript CG31122-RC
Echinococcus granulosus EgrG_001013200   expressed conserved protein
Echinococcus multilocularis EmuJ_001013200   expressed conserved protein
Homo sapiens ENSG00000178074   chromosome 2 open reading frame 69
Mus musculus ENSMUSG00000038323   RIKEN cDNA 1700066M21 gene
Plasmodium berghei PBANKA_1215200   conserved protein, unknown function
Plasmodium falciparum PF3D7_0323300   conserved protein, unknown function
Plasmodium knowlesi PKNH_0817100   conserved protein, unknown function
Plasmodium vivax PVX_095060   conserved protein, unknown function
Plasmodium yoelii PY00356   hypothetical protein
Schistosoma japonicum Sjp_0080370   similar to UPF0565 protein precursor, putative
Schistosoma mansoni Smp_172120   hypothetical protein

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier Smp_172120 (Schistosoma mansoni), hypothetical protein
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