Detailed view for PVX_241295

Basic information

TDR Targets ID: 322228
Plasmodium vivax, unspecified product
Source Database / ID:  PlasmoDB 

pI: 5.5838 | Length (AA): 489 | MW (Da): 54218 | Paralog Number: 34

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 1

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

No Pfam domain information for this protein.

Gene Ontology

Mouse over links to read term descriptions.
No GO information for this protein.

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There is 1 model calculated for this protein. More info on this model, including the model itself is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
13 231 4kik (B) 448 663 11.00 0 0.2 0.309953 -0.48

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_132974)

Species Accession Gene Product
Plasmodium vivax PVX_019165   unspecified product
Plasmodium vivax PVX_112125   unspecified product
Plasmodium vivax PVX_010100   unspecified product
Plasmodium vivax PVX_055190   unspecified product
Plasmodium vivax PVX_068190   unspecified product
Plasmodium vivax PVX_020675   unspecified product
Plasmodium vivax PVX_045190   unspecified product
Plasmodium vivax PVX_065190   unspecified product
Plasmodium vivax PVX_120335   unspecified product
Plasmodium vivax PVX_035690   unspecified product
Plasmodium vivax PVX_121855   variable surface protein Vir18, putative
Plasmodium vivax PVX_062690   unspecified product
Plasmodium vivax PVX_013625   unspecified product
Plasmodium vivax PVX_016640   unspecified product
Plasmodium vivax PVX_101625   variable surface protein Vir18-like
Plasmodium vivax PVX_124708   VIR protein
Plasmodium vivax PVX_104700   unspecified product
Plasmodium vivax PVX_017145   unspecified product
Plasmodium vivax PVX_004503   VIR protein
Plasmodium vivax PVX_083585   variable surface protein Vir18-related
Plasmodium vivax PVX_021180   unspecified product
Plasmodium vivax PVX_011110   unspecified product
Plasmodium vivax PVX_107230   unspecified product
Plasmodium vivax PVX_017650   unspecified product
Plasmodium vivax PVX_013120   unspecified product
Plasmodium vivax PVX_241295   unspecified product
Plasmodium vivax PVX_060690   unspecified product
Plasmodium vivax PVX_068690   unspecified product
Plasmodium vivax PVX_101617   VIR protein
Plasmodium vivax PVX_015640   unspecified product
Plasmodium vivax PVX_006080   unspecified product
Plasmodium vivax PVX_018150   unspecified product
Plasmodium vivax PVX_066190   unspecified product
Plasmodium vivax PVX_103150   variable surface protein Vir18, putative
Plasmodium vivax PVX_015130   unspecified product

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier PVX_241295 (Plasmodium vivax), unspecified product
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