pI: 6.1587 |
Length (AA): 287 |
MW (Da): 33397 |
Paralog Number:
114
Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0
Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable
Modbase 3D models:
There is 1 model calculated for this protein. More info on
this model, including the
model itself is available at:
Modbase
Target Beg | Target End | Template | Template Beg | Template End | Identity | Evalue | Model Score | MPQS | zDope |
---|---|---|---|---|---|---|---|---|---|
20 | 237 | 2aqw (A) | 3 | 216 | 12.00 | 0.41 | 0.19 | 0.860982 | -0.11 |
Help me make sense of these data.
A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.
PDB Structures:
Ortholog group members (OG5_127519)
Species | Accession | Gene Product |
---|---|---|
Caenorhabditis elegans | CELE_Y49E10.10 | Protein Y49E10.10 |
Plasmodium vivax | PVX_002485 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_017140 | unspecified product |
Plasmodium vivax | PVX_077695 | unspecified product |
Plasmodium vivax | PVX_107740 | unspecified product |
Plasmodium vivax | PVX_086865 | VIR protein |
Plasmodium vivax | PVX_065690 | unspecified product |
Plasmodium vivax | PVX_001635 | VIR protein |
Plasmodium vivax | PVX_074690 | unspecified product |
Plasmodium vivax | PVX_018660 | unspecified product |
Plasmodium vivax | PVX_124705 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_005045 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_108765 | unspecified product |
Plasmodium vivax | PVX_090310 | VIR protein |
Plasmodium vivax | PVX_119210 | variant surface protein Vir22/5/24, putative |
Plasmodium vivax | PVX_094245 | variable surface protein Vir12-like |
Plasmodium vivax | PVX_094240 | variable surface protein Vir12/24-related |
Plasmodium vivax | PVX_120845 | unspecified product |
Plasmodium vivax | PVX_023185 | unspecified product |
Plasmodium vivax | PVX_049690 | unspecified product |
Plasmodium vivax | PVX_041690 | unspecified product |
Plasmodium vivax | PVX_107755 | unspecified product |
Plasmodium vivax | PVX_005055 | VIR protein |
Plasmodium vivax | PVX_124720 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_007085 | unspecified product |
Plasmodium vivax | PVX_090315 | variable surface protein Vir12-like |
Plasmodium vivax | PVX_097555 | variable surface protein Vir12/16-related |
Plasmodium vivax | PVX_088805 | variable surface protein Vir22/24-like |
Plasmodium vivax | PVX_110295 | variable surface protein Vir22-like |
Plasmodium vivax | PVX_076195 | unspecified product |
Plasmodium vivax | PVX_042190 | unspecified product |
Plasmodium vivax | PVX_005060 | variable surface protein Vir12-like |
Plasmodium vivax | PVX_096920 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_015635 | unspecified product |
Plasmodium vivax | PVX_088780 | variable surface protein Vir24-related |
Plasmodium vivax | PVX_020170 | unspecified product |
Plasmodium vivax | PVX_061690 | unspecified product |
Plasmodium vivax | PVX_104180 | unspecified product |
Plasmodium vivax | PVX_002490 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_107745 | unspecified product |
Plasmodium vivax | PVX_183280 | unspecified product |
Plasmodium vivax | PVX_241290 | unspecified product |
Plasmodium vivax | PVX_090295 | VIR protein |
Plasmodium vivax | PVX_097530 | variable surface protein Vir22/12-related |
Plasmodium vivax | PVX_104190 | unspecified product |
Plasmodium vivax | PVX_097545 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_081850 | variable surface protein Vir22/23-related |
Plasmodium vivax | PVX_097525 | variable surface protein Vir 12, putative |
Plasmodium vivax | PVX_063190 | unspecified product |
Plasmodium vivax | PVX_133260 | unspecified product |
Plasmodium vivax | PVX_090305 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_004495 | VIR protein |
Plasmodium vivax | PVX_096910 | variable surface protein Vir23-related |
Plasmodium vivax | PVX_103155 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_010105 | unspecified product |
Plasmodium vivax | PVX_124715 | variable surface protein Vir5-related |
Plasmodium vivax | PVX_115490 | VIR protein |
Plasmodium vivax | PVX_022685 | unspecified product |
Plasmodium vivax | PVX_009595 | unspecified product |
Plasmodium vivax | PVX_078195 | unspecified product |
Plasmodium vivax | PVX_088795 | VIR protein |
Plasmodium vivax | PVX_093720 | variable surface protein Vir24-like |
Plasmodium vivax | PVX_003490 | VIR protein |
Plasmodium vivax | PVX_086895 | VIR protein |
Plasmodium vivax | PVX_112720 | unspecified product |
Plasmodium vivax | PVX_086893 | VIR protein |
Plasmodium vivax | PVX_093735 | VIR protein |
Plasmodium vivax | PVX_125726 | unspecified product |
Plasmodium vivax | PVX_027190 | unspecified product |
Plasmodium vivax | PVX_157260 | unspecified product |
Plasmodium vivax | PVX_086855 | variable surface protein Vir24-like |
Plasmodium vivax | PVX_001640 | VIR protein |
Plasmodium vivax | PVX_097542 | VIR protein |
Plasmodium vivax | PVX_110300 | variable surface protein Vir21, putative |
Plasmodium vivax | PVX_170270 | unspecified product |
Plasmodium vivax | PVX_086860 | variable surface protein Vir24-related |
Plasmodium vivax | PVX_037690 | unspecified product |
Plasmodium vivax | PVX_036690 | unspecified product |
Plasmodium vivax | PVX_001645 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_101630 | VIR protein |
Plasmodium vivax | PVX_024685 | unspecified product |
Plasmodium vivax | PVX_054190 | unspecified product |
Plasmodium vivax | PVX_090290 | variable surface protein Vir12, putative |
Plasmodium vivax | PVX_001625 | variable surface protein Vir12-related |
Plasmodium vivax | PVX_003505 | variable surface protein Vir24-related |
Plasmodium vivax | PVX_003495 | variable surface protein Vir22/24-related |
Plasmodium vivax | PVX_096003 | VIR protein |
Plasmodium vivax | PVX_172270 | unspecified product |
Plasmodium vivax | PVX_022185 | unspecified product |
Plasmodium vivax | PVX_083580 | variable surface protein Vir24-related |
Plasmodium vivax | PVX_034690 | unspecified product |
Plasmodium vivax | PVX_004537 | VIR protein |
Plasmodium vivax | PVX_115985 | unspecified product |
Plasmodium vivax | PVX_083590 | variable surface protein Vir12, putative |
Plasmodium vivax | PVX_106220 | variable surface protein Vir12, putative |
Plasmodium vivax | PVX_094250 | VIR protein |
Plasmodium vivax | PVX_038190 | unspecified product |
Plasmodium vivax | PVX_134260 | unspecified product |
Plasmodium vivax | PVX_075695 | unspecified product |
Plasmodium vivax | PVX_158260 | unspecified product |
Plasmodium vivax | PVX_124725 | VIR protein |
Plasmodium vivax | PVX_004530 | VIR protein |
Plasmodium vivax | PVX_013620 | unspecified product |
Plasmodium vivax | PVX_115480 | variable surface protein Vir21, putative |
Plasmodium vivax | PVX_003510 | variable surface protein Vir24-related |
Plasmodium vivax | PVX_107235 | unspecified product |
Plasmodium vivax | PVX_107735 | unspecified product |
Plasmodium vivax | PVX_020680 | unspecified product |
Plasmodium vivax | PVX_102640 | unspecified product |
Plasmodium vivax | PVX_002480 | variable surface protein Vir12/24-related |
Plasmodium vivax | PVX_074190 | unspecified product |
Plasmodium vivax | PVX_096001 | VIR protein |
Plasmodium vivax | PVX_005057 | VIR protein |
Plasmodium vivax | PVX_120340 | unspecified product |
Plasmodium vivax | PVX_106725 | unspecified product |
Plasmodium vivax | PVX_073690 | unspecified product |
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please contact us.