Detailed view for TVAG_367050

Basic information

TDR Targets ID: 836778
Trichomonas vaginalis, microsomal stress 70 protein ATPase core precursor, putative
Source Database / ID: 

pI: 5.5433 | Length (AA): 621 | MW (Da): 70207 | Paralog Number: 104

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00012   Hsp70 protein

Gene Ontology

Mouse over links to read term descriptions.
No GO information for this protein.

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_185694)

Species Accession Gene Product
Trichomonas vaginalis TVAG_RG_DS125941_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS123297_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS133062_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS132900_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS136621_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_TEG_DS113962_2_5   Maverick transposable element conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS151438_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS131657_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS141510_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS147318_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS144371_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS130668_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS147033_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS142495_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS125306_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS138392_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS147787_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS148577_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS121210_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS151164_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS134023_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS123268_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS136135_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_491770   heat shock protein 70kD, putative
Trichomonas vaginalis TVAG_RG_DS131882_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS113742_3   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS140841_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS150586_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS122454_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS137185_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_TEG_DS113216_4_8   Maverick transposable element conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS115332_3   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS139453_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS119300_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS133550_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS149607_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS126368_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS139273_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS118392_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS127281_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS135010_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS128405_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS122754_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS134501_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS131403_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS143592_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS117713_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS140586_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS130164_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS143784_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS140821_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS149223_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS139824_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS128284_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS141338_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS151818_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_TEG_DS113261_1_10   Maverick transposable element conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS139640_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS136871_1   hypothetical protein
Trichomonas vaginalis TVAG_RG_DS113598_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_264860   heat shock protein, putative
Trichomonas vaginalis TVAG_RG_DS132655_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS131145_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS131646_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS141255_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS136334_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS143605_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS127824_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS119625_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS125113_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS145738_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS115741_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS123114_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS133785_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_367050   microsomal stress 70 protein ATPase core precursor, putative
Trichomonas vaginalis TVAG_RG_DS127121_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS129790_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS132722_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS147647_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS135976_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS132066_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS115423_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS134011_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS119599_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS125710_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS134220_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS128863_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS121099_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS113304_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS151172_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS141865_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS135328_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS133345_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS115212_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS148675_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS137009_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS127487_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_307790   heat shock protein 70kD, putative
Trichomonas vaginalis TVAG_RG_DS126708_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS115270_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS133735_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS121243_3   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS149862_2   conserved hypothetical protein
Trichomonas vaginalis TVAG_RG_DS149456_1   conserved hypothetical protein
Trichomonas vaginalis TVAG_TEG_DS113506_1_4   Maverick transposable element conserved hypothetical protein

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
Species Target Length Identity Alignment span Linked Drugs Reference
Rattus norvegicus Thymidine kinase 121 aa 25.7% 109 aa Compounds References
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier TVAG_367050 (Trichomonas vaginalis), microsomal stress 70 protein ATPase core precursor, putative
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