Detailed view for TVAG_376240

Basic information

TDR Targets ID: 854996
Trichomonas vaginalis, inversin, putative
Source Database / ID: 

pI: 6.2281 | Length (AA): 546 | MW (Da): 62905 | Paralog Number: 23

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00023   Ankyrin repeat
PF12796   Ankyrin repeats (3 copies)
PF13606   Ankyrin repeat

Gene Ontology

Mouse over links to read term descriptions.
GO:0005515   protein binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_135074)

Species Accession Gene Product
Trichomonas vaginalis TVAG_105650   conserved hypothetical protein
Trichomonas vaginalis TVAG_075300   harmonin-interacting ankyrin-repeat containing protein (harp), sans, putative
Trichomonas vaginalis TVAG_271180   2-5A-dependent ribonuclease, putative
Trichomonas vaginalis TVAG_157400   harmonin-interacting ankyrin-repeat containing protein (harp), sans, putative
Trichomonas vaginalis TVAG_432000   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_065840   harmonin-interacting ankyrin-repeat containing protein (harp), sans, putative
Trichomonas vaginalis TVAG_381350   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_321380   cortactin-binding protein, putative
Trichomonas vaginalis TVAG_027780   serine/threonine-protein kinase ripk4, putative
Trichomonas vaginalis TVAG_403730   skeletrophin, putative
Trichomonas vaginalis TVAG_431990   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_134530   conserved hypothetical protein
Trichomonas vaginalis TVAG_134520   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_078560   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_027790   ankyrin repeat and FYVE domain containing protein, putative
Trichomonas vaginalis TVAG_260250   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_078550   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_053310   ankyrin repeat-rich membrane-spanning protein, putative
Trichomonas vaginalis TVAG_456670   homeobox-containing protein wariai, putative
Trichomonas vaginalis TVAG_182070   conserved hypothetical protein
Trichomonas vaginalis TVAG_347080   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_244470   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_140040   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_376240   inversin, putative

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier TVAG_376240 (Trichomonas vaginalis), inversin, putative
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