Detailed view for TVAG_374150

Basic information

TDR Targets ID: 861371
Trichomonas vaginalis, sucrose transport protein, putative
Source Database / ID: 

pI: 8.2057 | Length (AA): 469 | MW (Da): 51786 | Paralog Number: 15

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 12

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF07690   Major Facilitator Superfamily

Gene Ontology

Mouse over links to read term descriptions.
GO:0016021   integral to membrane  
GO:0055085   transmembrane transport  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_129015)

Species Accession Gene Product
Arabidopsis thaliana AT1G22710   sucrose transport protein SUC2
Arabidopsis thaliana AT1G66570   putative sucrose transport protein SUC7
Arabidopsis thaliana AT1G71890   sucrose transport protein SUC5
Arabidopsis thaliana AT1G71880   sucrose transport protein SUC1
Arabidopsis thaliana AT2G14670   sucrose transport protein SUC8
Arabidopsis thaliana AT5G43610   putative sucrose transport protein SUC6
Arabidopsis thaliana AT5G06170   sucrose transport protein SUC9
Arabidopsis thaliana AT1G09960   sucrose transporter 4
Dictyostelium discoideum DDB_G0267582   hypothetical protein
Dictyostelium discoideum DDB_G0276801   hypothetical protein
Entamoeba histolytica EHI_153450   transporter, major facilitator family
Oryza sativa 4348577   Os10g0404500
Oryza sativa 4331775   Os03g0170900
Oryza sativa 4329756   Os02g0576600
Trichomonas vaginalis TVAG_065760   conserved hypothetical protein
Trichomonas vaginalis TVAG_208600   conserved hypothetical protein
Trichomonas vaginalis TVAG_336290   conserved hypothetical protein
Trichomonas vaginalis TVAG_455540   sucrose transport protein, putative
Trichomonas vaginalis TVAG_186670   conserved hypothetical protein
Trichomonas vaginalis TVAG_209050   conserved hypothetical protein
Trichomonas vaginalis TVAG_009680   sucrose transport protein, putative
Trichomonas vaginalis TVAG_070900   sucrose transport protein, putative
Trichomonas vaginalis TVAG_361610   sucrose transport protein, putative
Trichomonas vaginalis TVAG_058420   sucrose transport protein, putative
Trichomonas vaginalis TVAG_065750   sucrose transport protein, putative
Trichomonas vaginalis TVAG_239840   sucrose transport protein, putative
Trichomonas vaginalis TVAG_039200   sucrose transport protein, putative
Trichomonas vaginalis TVAG_374150   sucrose transport protein, putative
Trichomonas vaginalis TVAG_474340   sucrose transport protein, putative
Trichomonas vaginalis TVAG_332440   sucrose transport protein, putative

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier TVAG_374150 (Trichomonas vaginalis), sucrose transport protein, putative
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