pI: 8.0094 |
Length (AA): 200 |
MW (Da): 23274 |
Paralog Number:
2
Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0
Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable
Modbase 3D models:
PDB Structures:
Ortholog group members (OG5_130848)
Species | Accession | Gene Product |
---|---|---|
Arabidopsis thaliana | AT5G16800 | GCN5-related N-acetyltransferase (GNAT) family protein |
Arabidopsis thaliana | AT3G02980 | meiotic control of crossovers1 protein |
Brugia malayi | Bm1_47710 | acetyltransferase, GNAT family protein |
Caenorhabditis elegans | CELE_F30F8.10 | Protein F30F8.10, isoform A |
Caenorhabditis elegans | CELE_F54E7.9 | Protein F54E7.9 |
Cryptosporidium hominis | Chro.80236 | GCN5-related N-acetyltransferase (GNAT) family |
Cryptosporidium parvum | cgd8_2010 | span like RimI family protein amino acetyltransferase |
Dictyostelium discoideum | DDB_G0289581 | GCN5-related N-acetyltransferase |
Drosophila melanogaster | Dmel_CG18177 | N(alpha)-acetyltransferase 60 |
Echinococcus granulosus | EgrG_000084400 | N alpha acetyltransferase 60 |
Entamoeba histolytica | EHI_187730 | acetyltransferase, GNAT family |
Echinococcus multilocularis | EmuJ_000084400 | |
Homo sapiens | ENSG00000122390 | N(alpha)-acetyltransferase 60, NatF catalytic subunit |
Loa Loa (eye worm) | LOAG_08250 | hypothetical protein |
Mus musculus | ENSMUSG00000005982 | N(alpha)-acetyltransferase 60, NatF catalytic subunit |
Oryza sativa | 9269142 | Os02g0694201 |
Schmidtea mediterranea | mk4.000675.06 | N-alpha-acetyltransferase 60 |
Schmidtea mediterranea | mk4.002125.06 | N-alpha-acetyltransferase 60 |
Trichomonas vaginalis | TVAG_096140 | N-terminal acetyltransferase, putative |
Trichomonas vaginalis | TVAG_169900 | N-terminal acetyltransferase, putative |
Trichomonas vaginalis | TVAG_123540 | N-acetyltransferase separation anxiety, putative |
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please contact us.