Detailed view for TVAG_389890

Basic information

TDR Targets ID: 884894
Trichomonas vaginalis, ankyrin repeat and FYVE domain containing protein, putative
Source Database / ID: 

pI: 7.0958 | Length (AA): 622 | MW (Da): 71617 | Paralog Number: 38

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00169   PH domain
PF12796   Ankyrin repeats (3 copies)

Gene Ontology

Mouse over links to read term descriptions.
GO:0005515   protein binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_131923)

Species Accession Gene Product
Dictyostelium discoideum DDB_G0272971   hypothetical protein
Trichomonas vaginalis TVAG_186650   homeobox-containing protein wariai, putative
Trichomonas vaginalis TVAG_474720   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_219930   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_211750   ion channel nompc, putative
Trichomonas vaginalis TVAG_295070   conserved hypothetical protein
Trichomonas vaginalis TVAG_460800   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_358280   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_482480   fibronectin type 3 and ankyrin repeat domains, putative
Trichomonas vaginalis TVAG_124860   conserved hypothetical protein
Trichomonas vaginalis TVAG_175620   ankyrin 2,3/unc44, putative
Trichomonas vaginalis TVAG_174070   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_219890   ankyrin repeat and socs box protein, putative
Trichomonas vaginalis TVAG_188610   ankyrin repeat domain protein, putative
Trichomonas vaginalis TVAG_447770   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_295350   ankyrin repeat domain protein, putative
Trichomonas vaginalis TVAG_019830   sex-determining protein fem-1, putative
Trichomonas vaginalis TVAG_395520   conserved hypothetical protein
Trichomonas vaginalis TVAG_204260   death- associated protein kinase, putative
Trichomonas vaginalis TVAG_005500   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_388150   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_207560   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_392130   conserved hypothetical protein
Trichomonas vaginalis TVAG_277740   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_429970   ankyrin repeat domain protein, putative
Trichomonas vaginalis TVAG_389890   ankyrin repeat and FYVE domain containing protein, putative
Trichomonas vaginalis TVAG_175660   ankyrin repeat and socs box protein, putative
Trichomonas vaginalis TVAG_551660   cardiac ankyrin repeat protein, putative
Trichomonas vaginalis TVAG_044830   conserved hypothetical protein
Trichomonas vaginalis TVAG_284550   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_451530   ankyrin repeat domain, putative
Trichomonas vaginalis TVAG_246940   cortactin-binding protein, putative
Trichomonas vaginalis TVAG_114730   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_345920   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_475360   ankyrin 2,3/unc44, putative
Trichomonas vaginalis TVAG_136990   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_476840   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_499230   ankyrin repeat domain, putative
Trichomonas vaginalis TVAG_475510   ankyrin repeat-containing protein, putative
Trichomonas vaginalis TVAG_474730   conserved hypothetical protein

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier TVAG_389890 (Trichomonas vaginalis), ankyrin repeat and FYVE domain containing protein, putative
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