Detailed view for TVAG_511260

Basic information

TDR Targets ID: 886853
Trichomonas vaginalis, conserved hypothetical protein
Source Database / ID: 

pI: 4.767 | Length (AA): 247 | MW (Da): 27547 | Paralog Number: 51

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

No Pfam domain information for this protein.

Gene Ontology

Mouse over links to read term descriptions.
GO:0005515   protein binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_130499)

Species Accession Gene Product
Plasmodium falciparum PF3D7_1201400   Plasmodium exported protein, unknown function
Trichomonas vaginalis TVAG_004700   neutral sphingomyelinase (N-smase) activation associated factor fan, putative
Trichomonas vaginalis TVAG_349540   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_242490   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_223710   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_107930   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_266330   conserved hypothetical protein
Trichomonas vaginalis TVAG_351710   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_271590   conserved hypothetical protein
Trichomonas vaginalis TVAG_183610   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_071440   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_225370   neurobeachin, putative
Trichomonas vaginalis TVAG_343650   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_404760   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_362310   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_189020   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_116260   neutral sphingomyelinase (N-smase) activation associated factor fan, putative
Trichomonas vaginalis TVAG_051890   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_511260   conserved hypothetical protein
Trichomonas vaginalis TVAG_225450   hypothetical protein
Trichomonas vaginalis TVAG_489220   lysosomal trafficking regulator, putative
Trichomonas vaginalis TVAG_107920   conserved hypothetical protein
Trichomonas vaginalis TVAG_420820   neurobeachin, putative
Trichomonas vaginalis TVAG_125440   conserved hypothetical protein
Trichomonas vaginalis TVAG_477030   neurobeachin, putative
Trichomonas vaginalis TVAG_071330   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_489230   conserved hypothetical protein
Trichomonas vaginalis TVAG_557080   conserved hypothetical protein
Trichomonas vaginalis TVAG_042020   conserved hypothetical protein
Trichomonas vaginalis TVAG_119700   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_087250   lysosomal trafficking regulator, putative
Trichomonas vaginalis TVAG_031070   conserved hypothetical protein
Trichomonas vaginalis TVAG_223750   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_239340   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_424040   neurobeachin, putative
Trichomonas vaginalis TVAG_161110   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_310940   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_065720   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_043560   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_465990   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_475690   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_468650   conserved hypothetical protein
Trichomonas vaginalis TVAG_332090   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_119530   neurobeachin, putative
Trichomonas vaginalis TVAG_299580   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_188790   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_066010   conserved hypothetical protein
Trichomonas vaginalis TVAG_125450   neurobeachin-like protein, putative
Trichomonas vaginalis TVAG_059960   neutral sphingomyelinase (N-smase) activation associated factor fan, putative
Trichomonas vaginalis TVAG_061450   neurobeachin, putative
Trichomonas vaginalis TVAG_374880   neutral sphingomyelinase (N-smase) activation associated factor fan, putative
Trichomonas vaginalis TVAG_148310   conserved hypothetical protein
Trichomonas vaginalis TVAG_374890   conserved hypothetical protein

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier TVAG_511260 (Trichomonas vaginalis), conserved hypothetical protein
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