Detailed view for TVAG_385560

Basic information

TDR Targets ID: 912348
Trichomonas vaginalis, inhibitor of growth, putative
Source Database / ID: 

pI: 4.941 | Length (AA): 203 | MW (Da): 23068 | Paralog Number: 1

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00628   PHD-finger

Gene Ontology

Mouse over links to read term descriptions.
No GO information for this protein.

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_128635)

Species Accession Gene Product
Arabidopsis thaliana AT3G24010   PHD finger protein ING1
Brugia malayi Bm1_08060   PHD-finger family protein
Candida albicans CaO19.8497   potential PHD finger protein similar to S. cerevisiae YNG2 (YHR090C) NuA4 histone acetyltransferase complex component
Candida albicans CaO19.878   potential PHD finger protein similar to S. cerevisiae YNG2 (YHR090C) NuA4 histone acetyltransferase complex component
Dictyostelium discoideum DDB_G0284411   PHD zinc finger-containing protein
Drosophila melanogaster Dmel_CG9293   CG9293 gene product from transcript CG9293-RB
Echinococcus granulosus EgrG_001048400   inhibitor of growth protein 4
Echinococcus granulosus EgrG_001048500   dna repair protein swi5
Echinococcus granulosus EgrG_000221500   inhibitor of growth protein 3
Echinococcus multilocularis EmuJ_001048400   inhibitor of growth protein 4
Echinococcus multilocularis EmuJ_001048500   dna repair protein swi5
Homo sapiens ENSG00000111653   inhibitor of growth family, member 4
Homo sapiens ENSG00000168395   inhibitor of growth family, member 5
Loa Loa (eye worm) LOAG_08679   PHD-finger family protein
Mus musculus ENSMUSG00000030330   inhibitor of growth family, member 4
Mus musculus ENSMUSG00000026283   inhibitor of growth family, member 5
Oryza sativa 4331591   Os03g0143600
Onchocerca volvulus OVOC5886  
Saccharomyces cerevisiae YHR090C   Yng2p
Schistosoma japonicum Sjp_0214440   expressed protein
Schistosoma japonicum Sjp_0214430   Inhibitor of growth protein 4, putative
Schistosoma mansoni Smp_120980   inhibitor of growth family member 5
Schmidtea mediterranea mk4.000093.03   Inhibitor of growth protein 3
Schmidtea mediterranea mk4.022181.00  
Schmidtea mediterranea mk4.000263.08  
Schmidtea mediterranea mk4.011423.00   Ing-related
Schmidtea mediterranea mk4.021903.00  
Schmidtea mediterranea mk4.000093.00   Inhibitor of growth protein 3
Schmidtea mediterranea mk4.000430.07  
Trichomonas vaginalis TVAG_021600   inhibitor of growth, putative
Trichomonas vaginalis TVAG_385560   inhibitor of growth, putative

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

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User comments

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Gene identifier TVAG_385560 (Trichomonas vaginalis), inhibitor of growth, putative
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