pI: 10.1482 |
Length (AA): 189 |
MW (Da): 21703 |
Paralog Number:
5
Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0
Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable
Modbase 3D models:
There are 3 models calculated for this protein. More info on
these models, including the
models themselves is available at:
Modbase
Target Beg | Target End | Template | Template Beg | Template End | Identity | Evalue | Model Score | MPQS | zDope |
---|---|---|---|---|---|---|---|---|---|
1 | 160 | 1u53 (A) | 7 | 188 | 27.00 | 0 | 1 | 1.06546 | -0.18 |
3 | 148 | 5vhg (A) | 7 | 153 | 38.00 | 0 | 1 | 1.27849 | -1.05 |
5 | 146 | 5jys (A) | 162 | 297 | 43.00 | 0 | 1 | 1.30032 | -0.98 |
Help me make sense of these data.
A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.
PDB Structures:
Ortholog group members (OG5_127576)
Species | Accession | Gene Product |
---|---|---|
Arabidopsis thaliana | AT4G33720 | putative pathogenesis-related protein |
Arabidopsis thaliana | AT1G50060 | putative pathogenesis-related protein |
Babesia bovis | BBOV_III003800 | SCP-like extracellular protein family protein |
Brugia malayi | Bm1_51135 | SCP-like extracellular protein |
Candida albicans | CaO19.7218 | potential SCP-like extracellular protein similar to S. cerevisiae PRY2 (YKR013W) plant Pathogen Related PR-1 class of proteins |
Candida albicans | CaO19.6200 | similar to C. albicans RBT4p |
Candida albicans | CaO19.13580 | similar to C. albicans RBT4p |
Caenorhabditis elegans | CELE_C07A4.3 | Protein C07A4.3 |
Caenorhabditis elegans | CELE_F57B7.2 | Protein F57B7.2, isoform A |
Dictyostelium discoideum | DDB_G0286055 | hypothetical protein |
Drosophila melanogaster | Dmel_CG42764 | CG42764 gene product from transcript CG42764-RB |
Drosophila melanogaster | Dmel_CG4270 | CG4270 gene product from transcript CG4270-RA |
Drosophila melanogaster | Dmel_CG31482 | CG31482 gene product from transcript CG31482-RA |
Drosophila melanogaster | Dmel_CG16995 | CG16995 gene product from transcript CG16995-RA |
Echinococcus granulosus | EgrG_000745100 | venom allergen val protein |
Echinococcus granulosus | EgrG_000745000 | venom allergen val protein |
Echinococcus granulosus | EgrG_000373100 | venom allergen (val) protein |
Echinococcus granulosus | EgrG_000376100 | Golgi associated plant pathogenesis |
Echinococcus granulosus | EgrG_000376000 | Golgi associated plant pathogenesis |
Echinococcus granulosus | EgrG_000373200 | 5'partial|venom allergen val protein |
Echinococcus multilocularis | EmuJ_000373100 | Golgi associated plant pathogenesis |
Echinococcus multilocularis | EmuJ_000376000 | Golgi associated plant pathogenesis |
Echinococcus multilocularis | EmuJ_000745000 | venom allergen (val) protein |
Echinococcus multilocularis | EmuJ_000376100 | Golgi associated plant pathogenesis |
Echinococcus multilocularis | EmuJ_000373200 | venom allergen (val) protein |
Echinococcus multilocularis | EmuJ_000745100 | venom allergen (val) protein |
Homo sapiens | ENSG00000122694 | GLI pathogenesis-related 2 |
Loa Loa (eye worm) | LOAG_01011 | hypothetical protein |
Mus musculus | ENSMUSG00000028480 | GLI pathogenesis-related 2 |
Oryza sativa | 4335393 | Os04g0289600 |
Oryza sativa | 4352877 | Os12g0633400 |
Onchocerca volvulus | OVOC12845 |
|
Onchocerca volvulus | OVOC12902 |
|
Onchocerca volvulus | OVOC6972 |
|
Plasmodium falciparum | PF3D7_0705800 | cysteine-rich secretory protein, putative |
Plasmodium knowlesi | PKNH_0104300 | cysteine-rich secretory protein, putative |
Plasmodium vivax | PVX_087830 | cysteine-rich secretory protein, putative |
Saccharomyces cerevisiae | YKR013W | Pry2p |
Saccharomyces cerevisiae | YJL079C | Pry1p |
Schistosoma japonicum | Sjp_0000390 | IPR001283,Allergen V5/Tpx-1 related,domain-containing |
Schistosoma japonicum | Sjp_0000400 | Golgi-associated plant pathogenesis-related protein 1, putative |
Schistosoma japonicum | Sjp_0000410 | Golgi-associated plant pathogenesis-related protein 1, putative |
Schistosoma japonicum | Sjp_0110620 | expressed protein |
Schistosoma japonicum | Sjp_0314330 | expressed protein |
Schistosoma japonicum | Sjp_0204830 | Golgi-associated plant pathogenesis-related protein 1, putative |
Schistosoma mansoni | Smp_124070 | venom allergen-like (VAL) 16 protein |
Schistosoma mansoni | Smp_124050.1 | venom allergen-like (VAL) 6 protein |
Schistosoma mansoni | Smp_163400 | venom allergen-like (VAL) 17 protein |
Schistosoma mansoni | Smp_124050.3 | venom allergen-like (VAL) 6 protein |
Schistosoma mansoni | Smp_124060 | venom allergen-like (VAL) 13 protein |
Schistosoma mansoni | Smp_124050.4 | venom allergen-like (VAL) 6 protein |
Schmidtea mediterranea | mk4.017597.01 | |
Schmidtea mediterranea | mk4.010442.01 | |
Schmidtea mediterranea | mk4.014829.00 | |
Schmidtea mediterranea | mk4.002396.04 | |
Schmidtea mediterranea | mk4.001499.02 | Golgi-associated plant pathogenesis-related protein 1 |
Schmidtea mediterranea | mk4.000278.05 | |
Schmidtea mediterranea | mk4.026268.03 | |
Schmidtea mediterranea | mk4.000830.09 |
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please contact us.