pI: 6.1904 |
Length (AA): 98 |
MW (Da): 10653 |
Paralog Number:
3
Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 2
Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable
Modbase 3D models:
PDB Structures:
Ortholog group members (OG5_138302)
Species | Accession | Gene Product |
---|---|---|
Brugia malayi | Bm1_37475 | Major Facilitator Superfamily protein |
Caenorhabditis elegans | CELE_K05B2.5 | Protein PES-22, isoform A |
Drosophila melanogaster | Dmel_CG13907 | CG13907 gene product from transcript CG13907-RA |
Echinococcus granulosus | EgrG_000420800 | 3'partial|Monocarboxylate transporter 14 |
Echinococcus granulosus | EgrG_000119300 | monocarboxylate transporter |
Echinococcus granulosus | EgrG_000882200 | Patterned Expression Site family member |
Echinococcus granulosus | EgrG_000412800 | monocarboxylate transporter |
Echinococcus multilocularis | EmuJ_000119300 | monocarboxylate transporter |
Echinococcus multilocularis | EmuJ_000358600 | monocarboxylate transporter |
Echinococcus multilocularis | EmuJ_000882200 | Patterned Expression Site family member |
Echinococcus multilocularis | EmuJ_000412800 | monocarboxylate transporter |
Loa Loa (eye worm) | LOAG_02432 | hypothetical protein |
Schistosoma japonicum | Sjp_0069690 | Monocarboxylate transporter 1, putative |
Schistosoma mansoni | Smp_161850 | monocarboxylate transporter |
Schmidtea mediterranea | mk4.031894.00 | |
Schmidtea mediterranea | mk4.002063.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.016171.01 | |
Schmidtea mediterranea | mk4.028519.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.028035.01 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.025433.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.025678.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.023948.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.001479.01 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.001267.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.002063.02 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.023948.01 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.009660.01 | |
Schmidtea mediterranea | mk4.016594.00 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.002063.03 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.005654.01 | EG:103B4.3 protein |
Schmidtea mediterranea | mk4.002661.07 | EG:103B4.3 protein |
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please contact us.