Detailed view for Sjp_0314900

Basic information

TDR Targets ID: 977584
Schistosoma japonicum, Fatty acid-binding protein, putative
Source Database / ID:  Wormbase Parasite  

pI: 9.2241 | Length (AA): 126 | MW (Da): 14275 | Paralog Number: 1

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00061   Lipocalin / cytosolic fatty-acid binding protein family

Gene Ontology

Mouse over links to read term descriptions.
GO:0008289   lipid binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_129604)

Species Accession Gene Product
Caenorhabditis elegans CELE_W02D3.7   Protein LBP-5
Caenorhabditis elegans CELE_W02D3.5   Protein LBP-6
Drosophila melanogaster Dmel_CG6783   fatty acid bindin protein
Echinococcus granulosus EgrG_000549800   fatty acid binding protein FABP2
Echinococcus granulosus EgrG_000550000   fatty acid binding protein, adipocyte
Echinococcus granulosus EgrG_000417200   fatty acid binding protein FABP2
Echinococcus granulosus EgrG_000549850   fatty acid binding protein FABP2
Echinococcus multilocularis EmuJ_000549800   fatty acid binding protein FABP2
Echinococcus multilocularis EmuJ_000417200   fatty acid binding protein FABP2
Echinococcus multilocularis EmuJ_000550000   fatty acid binding protein FABP2
Homo sapiens ENSG00000164434   fatty acid binding protein 7, brain
Homo sapiens 2170   fatty acid binding protein 3, muscle and heart
Homo sapiens ENSG00000147588   peripheral myelin protein 2
Mus musculus 14077   fatty acid binding protein 3, muscle and heart
Mus musculus ENSMUSG00000052468   peripheral myelin protein 2
Mus musculus ENSMUSG00000019874   fatty acid binding protein 7, brain
Schistosoma japonicum Sjp_0200770   ko:K08756 fatty acid-binding protein 7, brain, putative
Schistosoma japonicum Sjp_0314900   Fatty acid-binding protein, putative
Schistosoma mansoni Smp_095360.4   fatty acid binding protein
Schistosoma mansoni Smp_095360.1   fatty acid binding protein
Schmidtea mediterranea mk4.002794.04  

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Homo sapiens fatty acid binding protein 3, muscle and heart Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier Sjp_0314900 (Schistosoma japonicum), Fatty acid-binding protein, putative
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