Summary of available data:

As you can imagine, some types of data are not available for all organisms in TDR Targets (genome-wide knockouts is a good example). The reasons for this may vary: sometimes this is because the experimental data is lacking for a particular organism, sometimes it's because we need to process and check the data before loading; and yet sometimes it's because gathering and/or production of data is slow, as is the case for the manual curation of target validation credentials. In the table below we have tried to summarize the current status of data availability for each organism in TDR Targets.

If your queries are returning zero genes, you are probably searching on an attribute for which we have no data. Please check the table below for more details.

genome-wide data available
data available for a subset of the genome

Parent Group Organism Genes Essential
genes
Curated
targets
PDB
Structures
Modbase
models
Pfam
domains
EC
numbers
GO
terms
Druggability Pathways Assayability Antigenicity
Bacteria Mycobacterium tuberculosis 4049
Protist - Apicomplexa Plasmodium falciparum 5590  
Protist - Kinetoplastida Leishmania major 9222  
Protist - Kinetoplastida Trypanosoma brucei 10965
Protist - Kinetoplastida Trypanosoma cruzi 25013    
Bacteria Wolbachia endosymbiont of Brugia malayi 805        
Bacteria Mycobacterium leprae 1608    
Helminth - Nematoda Brugia malayi 11508        
Protist - Apicomplexa Toxoplasma gondii 8032    
Protist - Apicomplexa Plasmodium vivax 5446    
Helminth - Trematoda Schistosoma mansoni 13263            
Helminth - Nematoda Onchocerca volvulus Coming soon.