Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histamine receptor H3 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0098 | 0.9845 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0925 | 0.0925 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0098 | 0.9845 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0098 | 0.9845 | 0.9845 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0098 | 0.9845 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.314 | 0.3189 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0925 | 0.0925 |
Giardia lamblia | Kinase, PLK | 0.0098 | 0.9845 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0098 | 0.9845 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.9845 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0098 | 0.9845 | 0.9845 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0925 | 0.0939 |
Trypanosoma brucei | polo-like protein kinase | 0.0098 | 0.9845 | 0.5 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.1721 | 0.1721 |
Schistosoma mansoni | kinase | 0.005 | 0.2842 | 0.2887 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0098 | 0.9845 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0925 | 0.0939 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0925 | 0.0939 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.9845 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.468 | 0.4754 |
Schistosoma mansoni | jumonji domain containing protein | 0.0079 | 0.7041 | 0.7152 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0098 | 0.9845 | 0.9845 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0925 | 0.0925 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0098 | 0.9845 | 0.5 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.1721 | 0.1721 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.