Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
504 records found | Showing page 18 of 21 (records 426-450) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3367 | OG5_129879 | PE-PGRS family protein PE_PGRS51 |
| M. tuberculosis | Rv3389c | OG5_129142 | Probable 3-hydroxyacyl-thioester dehydratase HtdY |
| M. tuberculosis | Rv3392c | OG5_127897 | Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid s ... |
| M. tuberculosis | Rv3406 | OG5_129515 | Probable dioxygenase |
| M. tuberculosis | Rv3411c | OG5_126887 | Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosi ... |
| M. tuberculosis | Rv3413c | No group | Unknown alanine and proline rich protein |
| M. tuberculosis | Rv3414c | OG5_171008 | Probable alternative RNA polymerase sigma-D factor SigD |
| M. tuberculosis | Rv3416 | OG5_237579 | Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster. |
| M. tuberculosis | Rv3417c | OG5_127343 | 60 kDa chaperonin 1 GroEL1 (protein CPN60-1) (GroEL protein 1) |
| M. tuberculosis | Rv3425 | OG5_204794 | PPE family protein PPE57 |
| M. tuberculosis | Rv3429 | OG5_204794 | PPE family protein PPE59 |
| M. tuberculosis | Rv3457c | OG5_130460 | Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha cha ... |
| M. tuberculosis | Rv3462c | OG5_130791 | Probable translation initiation factor if-1 InfA |
| M. tuberculosis | Rv3465 | OG5_132926 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimer ... |
| M. tuberculosis | Rv3469c | OG5_155516 | Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA) |
| M. tuberculosis | Rv3472 | OG5_239167 | Conserved protein |
| M. tuberculosis | Rv3488 | OG5_159043 | Conserved hypothetical protein |
| M. tuberculosis | Rv3504 | OG5_239169 | Probable acyl-CoA dehydrogenase FadE26 |
| M. tuberculosis | Rv3505 | OG5_239170 | Probable acyl-CoA dehydrogenase FadE27 |
| M. tuberculosis | Rv3511 | OG5_129879 | PE-PGRS family protein PE_PGRS55 |
| M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
| M. tuberculosis | Rv3529c | OG5_182279 | Conserved hypothetical protein |
| M. tuberculosis | Rv3532 | OG5_135481 | PPE family protein PPE61 |
| M. tuberculosis | Rv3534c | OG5_155516 | Probable 4-hydroxy-2-oxovalerate aldolase (HOA) |
| M. tuberculosis | Rv3535c | OG5_179417 | Probable acetaldehyde dehydrogenase (acetaldehyde dehydrogenase [acetylating]) |