Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
491 records found | Showing page 19 of 20 (records 451-475) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3535c | OG5_179417 | Probable acetaldehyde dehydrogenase (acetaldehyde dehydrogenase [acetylating]) |
| M. tuberculosis | Rv3538 | OG5_129142 | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. |
| M. tuberculosis | Rv3544c | OG5_239170 | Probable acyl-CoA dehydrogenase FadE28 |
| M. tuberculosis | Rv3546 | No group | Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase) |
| M. tuberculosis | Rv3550 | No group | Probable enoyl-CoA hydratase EchA20 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv3556c | OG5_147360 | Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) |
| M. tuberculosis | Rv3610c | OG5_126616 | Membrane-bound protease FtsH (cell division protein) |
| M. tuberculosis | Rv3612c | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv3617 | OG5_129061 | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv3622c | OG5_132981 | PE family protein PE32 |
| M. tuberculosis | Rv3638 | OG5_129828 | Possible transposase |
| M. tuberculosis | Rv3659c | OG5_130713 | Conserved hypothetical protein |
| M. tuberculosis | Rv3660c | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv3663c | OG5_134183 | Probable dipeptide-transport ATP-binding protein ABC transporter DppD |
| M. tuberculosis | Rv3665c | OG5_128014 | Probable dipeptide-transport integral membrane protein ABC transporter DppB |
| M. tuberculosis | Rv3699 | OG5_139036 | Conserved protein |
| M. tuberculosis | Rv3706c | OG5_239173 | Conserved hypothetical proline rich protein |
| M. tuberculosis | Rv3714c | OG5_166866 | Conserved hypothetical protein |
| M. tuberculosis | Rv3736 | OG5_156161 | Transcriptional regulatory protein (probably AraC/XylS-family) |
| M. tuberculosis | Rv3741c | No group | Possible oxidoreductase |
| M. tuberculosis | Rv3744 | OG5_129305 | Metal sensor transcriptional regulator (ArsR-SmtB family) |
| M. tuberculosis | Rv3745c | OG5_145728 | Conserved hypothetical protein |
| M. tuberculosis | Rv3746c | OG5_239180 | Probable PE family protein PE34 (PE family-related protein) |
| M. tuberculosis | Rv3750c | OG5_239175 | Possible excisionase |
| M. tuberculosis | Rv3766 | No group | Hypothetical protein |