Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
460 records found | Showing page 6 of 19 (records 126-150) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv1185c | OG5_127582 | Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AM ... |
| M. tuberculosis | Rv1187 | OG5_128522 | Probable pyrroline-5-carboxylate dehydrogenase RocA |
| M. tuberculosis | Rv1188 | OG5_171183 | Probable proline dehydrogenase |
| M. tuberculosis | Rv1208 | OG5_152596 | Probable glucosyl-3-phosphoglycerate synthase GpgS |
| M. tuberculosis | Rv1229c | OG5_126620 | Probable Mrp-related protein Mrp |
| M. tuberculosis | Rv1232c | OG5_187206 | Conserved protein |
| M. tuberculosis | Rv1238 | OG5_128894 | Probable sugar-transport ATP-binding protein ABC transporter SugC |
| M. tuberculosis | Rv1250 | OG5_130801 | Probable drug-transport integral membrane protein |
| M. tuberculosis | Rv1254 | OG5_208500 | Probable acyltransferase |
| M. tuberculosis | Rv1256c | OG5_132455 | Probable cytochrome P450 130 Cyp130 |
| M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD |
| M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... |
| M. tuberculosis | Rv1295 | OG5_130923 | Threonine synthase ThrC (ts) |
| M. tuberculosis | Rv1296 | OG5_129171 | Probable homoserine kinase ThrB |
| M. tuberculosis | Rv1298 | OG5_130711 | 50S ribosomal protein L31 RpmE |
| M. tuberculosis | Rv1299 | OG5_126947 | Probable peptide chain release factor 1 PrfA (RF-1) |
| M. tuberculosis | Rv1300 | OG5_128078 | Probable HemK protein homolog HemK |
| M. tuberculosis | Rv1305 | OG5_126818 | Probable ATP synthase C chain AtpE (lipid-binding protein) (dicyclohexylcarbodii ... |
| M. tuberculosis | Rv1306 | OG5_134191 | Probable ATP synthase B chain AtpF |
| M. tuberculosis | Rv1307 | OG5_134191 | Probable ATP synthase delta chain AtpH |
| M. tuberculosis | Rv1308 | OG5_127165 | Probable ATP synthase alpha chain AtpA |
| M. tuberculosis | Rv1309 | OG5_127077 | Probable ATP synthase gamma chain AtpG |
| M. tuberculosis | Rv1310 | OG5_127099 | Probable ATP synthase beta chain AtpD |
| M. tuberculosis | Rv1311 | OG5_127404 | Probable ATP synthase epsilon chain AtpC |
| M. tuberculosis | Rv1326c | OG5_127579 | 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) |