Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 89 of 91 (records 2201-2225) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| M. tuberculosis | Rv3060c | OG5_153446 | Probable transcriptional regulatory protein (probably GntR-family) | -11 |
| M. tuberculosis | Rv3535c | OG5_179417 | Probable acetaldehyde dehydrogenase (acetaldehyde dehydrogenase [acetylating]) | -11 |
| M. tuberculosis | Rv3656c | No group | Conserved hypothetical protein | -11 |
| M. tuberculosis | Rv3789 | OG5_216766 | GTRA family protein | -11 |
| M. tuberculosis | Rv3895c | No group | ESX conserved component EccB2. ESX-2 type VII secretion system protein. Probable ... | -11 |
| M. tuberculosis | Rv0033 | No group | Probable acyl carrier protein AcpA (ACP) | -12 |
| M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... | -12 |
| M. tuberculosis | Rv3543c | OG5_239169 | Probable acyl-CoA dehydrogenase FadE29 | -12 |
| M. tuberculosis | Rv3859c | OG5_126892 | Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L ... | -12 |
| M. tuberculosis | Rv1663 | No group | Probable polyketide synthase Pks17 | -12 |
| M. tuberculosis | Rv3136 | OG5_135481 | PPE family protein PPE51 | -12 |
| M. tuberculosis | Rv3350c | OG5_132376 | PPE family protein PPE56 | -12 |
| M. tuberculosis | Rv0259c | OG5_133515 | Conserved hypothetical protein | -12 |
| M. tuberculosis | Rv0311 | No group | Unknown protein | -12 |
| M. tuberculosis | Rv0458 | OG5_126638 | Probable aldehyde dehydrogenase | -12 |
| M. tuberculosis | Rv0626 | OG5_239118 | Possible antitoxin VapB5 | -12 |
| M. tuberculosis | Rv1455 | No group | Conserved protein | -12 |
| M. tuberculosis | Rv1892 | No group | Probable membrane protein | -12 |
| M. tuberculosis | Rv1903 | OG5_150517 | Probable conserved membrane protein | -12 |
| M. tuberculosis | Rv2169c | OG5_237633 | Probable conserved transmembrane protein | -12 |
| M. tuberculosis | Rv2229c | OG5_209989 | Conserved protein | -12 |
| M. tuberculosis | Rv2358 | OG5_155588 | Probable transcriptional regulatory protein SmtB (probably ArsR-family) | -12 |
| M. tuberculosis | Rv2488c | OG5_160474 | Probable transcriptional regulatory protein (LuxR-family) | -12 |
| M. tuberculosis | Rv2527 | OG5_173651 | Possible toxin VapC17 | -12 |
| M. tuberculosis | Rv2683 | OG5_237449 | Conserved protein | -12 |