Target list

Search results for query: Union of (49, 50, 52, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 67, 68, 69, 70, 71, 72, 73, 81)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #61 (tcr > 2 paralogs): -18
  • Score for genes in query #55 (tcr doesn't have ortholog in mammals): 12
  • Score for genes in query #71 (is enzyme): 15
  • Score for genes in query #68 (ortholog essential in M. tuberculosis): 12
  • Score for genes in query #73 (has 3D structure(s)): 20
  • Score for genes in query #60 (has >= 1 TM domain): -3
  • Score for genes in query #81 (nucleotide-diversity-normalized): var
  • Score for genes in query #67 (ortholog essential in E. coli): 12
  • Score for genes in query #63 (has Signal Peptide): -3
  • Score for genes in query #62 (has GPI anchor signal): -3
  • Score for genes in query #64 (has EC number): 9
  • Score for genes in query #58 (Pubmed): 12
  • Score for genes in query #70 (ortholog in C. elegans has 'embryonic arrest' RNAi phenotype): 12
  • Score for genes in query #50 (tcr expression trypos-amas 1,5 fold 0.8 confidence): 12
  • Score for genes in query #57 (Assayability - Soluble): 7
  • Score for genes in query #59 (tcr MW < 100 kDa): 9
  • Score for genes in query #69 (ortholog essential in S. cerevisiae): 12
  • Score for genes in query #49 ( tcr expression epis-amas 1,5 fold 0.8 confidence): 12
  • Score for genes in query #56 (Assayability - Assay Available): 7
  • Score for genes in query #72 (has 3D model(s)): 20
  • Score for genes in query #52 (tcr has ortholog in kinetoplastida): 9

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18625 records found | Showing page 745 of 745 (records 18601-18625) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.507827.10   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.506111.20   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.511767.20   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.507477.10   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.508573.120   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.510175.60   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.509287.140   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.511827.130   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.507691.20   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.508325.30   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.509627.10   OG5_173566   hook complex protein, conserved -12
T. cruzi   TcCLB.507643.50   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.507719.9   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -12
T. cruzi   TcCLB.511677.10   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.462761.16   OG5_128471   Protein of unknown function (DUF423), putative -15
T. cruzi   TcCLB.505171.20   OG5_132347   hypothetical protein -15
T. cruzi   TcCLB.506523.9   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.508023.140   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.506961.50   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.507921.9   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.503655.20   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.508803.19   OG5_126612   dispersed gene family protein 1 (DGF-1), putative -15
T. cruzi   TcCLB.508823.10   OG5_128471   hypothetical protein, conserved -18
T. cruzi   TcCLB.511201.49   OG5_128471   Protein of unknown function (DUF423), putative -18
T. cruzi   TcCLB.509825.20   OG5_129277   hypothetical protein, conserved -18

Showing page 745 (records 18601-18625) of 745