Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0047 | 0.0432 | 0.0432 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1084 | 0.1084 |
Echinococcus granulosus | jun protein | 0.0081 | 0.1231 | 0.1231 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0456 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3248 | 0.3248 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.1081 | 0.1081 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0114 | 0.2002 | 0.2002 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0081 | 0.1231 | 0.1231 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.1535 | 0.3627 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0142 | 0.0335 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3248 | 0.3248 |
Brugia malayi | bZIP transcription factor family protein | 0.0081 | 0.1231 | 0.2908 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.1535 | 0.1535 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1179 | 0.1179 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0142 | 0.0142 |
Onchocerca volvulus | 0.0064 | 0.0822 | 0.6766 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0719 | 0.0719 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0047 | 0.0432 | 0.1021 |
Echinococcus granulosus | geminin | 0.0168 | 0.3248 | 0.3248 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0874 | 0.0874 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0081 | 0.1214 | 0.1214 |
Schistosoma mansoni | lipoxygenase | 0.008 | 0.1196 | 0.1196 |
Onchocerca volvulus | 0.0081 | 0.1214 | 1 | |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0456 | 1 | 1 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0456 | 1 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.1535 | 0.1535 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0114 | 0.2002 | 0.2002 |
Onchocerca volvulus | 0.0081 | 0.1214 | 1 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0142 | 0.0142 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0822 | 0.1941 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0142 | 0.0142 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0081 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0142 | 0.0142 |
Schistosoma mansoni | lipoxygenase | 0.0114 | 0.2002 | 0.2002 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0264 | 0.0264 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1214 | 0.1214 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0 | 0.5 |
Schistosoma mansoni | jun-related protein | 0.0066 | 0.0874 | 0.0874 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0142 | 0.0142 |
Echinococcus multilocularis | jun protein | 0.0081 | 0.1231 | 0.1231 |
Brugia malayi | Cation transporter family protein | 0.0081 | 0.1214 | 0.2869 |
Onchocerca volvulus | 0.0081 | 0.1214 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0482 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1214 | 0.1214 |
Brugia malayi | hypothetical protein | 0.021 | 0.4233 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0264 | 0.0264 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0081 | 0.1214 | 0.1214 |
Echinococcus multilocularis | geminin | 0.0168 | 0.3248 | 0.3248 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.