Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 1 (brain) | Starlite/ChEMBL | References |
Homo sapiens | cannabinoid receptor 2 (macrophage) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0232 | 0.2631 | 0.2631 |
Toxoplasma gondii | kringle domain-containing protein | 0.0261 | 0.3128 | 1 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.066 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.066 | 1 | 1 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Onchocerca volvulus | 0.0581 | 0.8628 | 0.8628 | |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1146 | 0.1146 |
Onchocerca volvulus | 0.0234 | 0.2652 | 0.2652 | |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0261 | 0.3128 | 0.3128 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0094 | 0.0244 | 0.0244 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0094 | 0.0244 | 0.0244 |
Brugia malayi | Protein kinase domain containing protein | 0.0261 | 0.3128 | 0.3128 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.1146 | 0.3665 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.2652 | 0.5 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0261 | 0.3128 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.3128 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.066 | 1 | 1 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.2163 | 0.2163 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.1146 | 0.3665 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Loa Loa (eye worm) | hypothetical protein | 0.066 | 1 | 1 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1146 | 0.1146 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0261 | 0.3128 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.0232 | 0.2631 | 0.2631 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0261 | 0.3128 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3128 | 0.3128 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0244 | 0.0244 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.1146 | 0.1146 |
Brugia malayi | Kringle domain containing protein | 0.0261 | 0.3128 | 0.3128 |
Mycobacterium ulcerans | hypothetical protein | 0.008 | 0 | 0.5 |
Onchocerca volvulus | 0.0261 | 0.3128 | 0.3128 | |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.2163 | 0.2163 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.1146 | 0.3665 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0261 | 0.3128 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0261 | 0.3128 | 0.3128 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0261 | 0.3128 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.066 | 1 | 1 |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0094 | 0.0244 | 0.0244 | |
Brugia malayi | PAN domain containing protein | 0.0094 | 0.0244 | 0.0244 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.