Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0375 | 0.0375 |
Onchocerca volvulus | 0.003 | 0.3537 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.3397 | 0.3397 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.5545 | 0.5545 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.3537 | 0.3537 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0375 | 0.0375 |
Schistosoma mansoni | lamin | 0.003 | 0.3537 | 0.6116 |
Echinococcus granulosus | lamin | 0.003 | 0.3537 | 1 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.3537 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0375 | 0.0375 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.3537 | 0.6116 |
Brugia malayi | intermediate filament protein | 0.003 | 0.3537 | 0.3537 |
Echinococcus multilocularis | musashi | 0.003 | 0.3537 | 1 |
Schistosoma mansoni | lamin | 0.003 | 0.3537 | 0.6116 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.3537 | 0.3537 |
Echinococcus multilocularis | lamin | 0.003 | 0.3537 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0375 | 0.0375 |
Onchocerca volvulus | 0.003 | 0.3537 | 0.5 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.3537 | 0.3537 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.5545 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.3537 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.3537 | 0.3537 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.5545 | 0.5545 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.3537 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.