Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0079 | 1 | 1 | |
Trypanosoma brucei | hexokinase | 0.0079 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0079 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0049 | 0.4548 | 0.4548 |
Loa Loa (eye worm) | hexokinase | 0.0079 | 1 | 1 |
Plasmodium falciparum | hexokinase | 0.0079 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.0079 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.5349 | 0.5349 |
Brugia malayi | hexokinase type II | 0.0025 | 0.0022 | 0.0022 |
Toxoplasma gondii | hexokinase | 0.0079 | 1 | 1 |
Onchocerca volvulus | 0.0079 | 1 | 1 | |
Loa Loa (eye worm) | hexokinase type II | 0.0079 | 1 | 1 |
Schistosoma mansoni | hexokinase | 0.0079 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase type 2 | 0.0079 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0079 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0022 | 0.0022 |
Echinococcus multilocularis | hexokinase | 0.0079 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0079 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0079 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.0079 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 2 | 0.0079 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0079 | 1 | 1 |
Onchocerca volvulus | 0.0079 | 1 | 1 | |
Plasmodium vivax | hexokinase, putative | 0.0079 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0049 | 0.4548 | 0.4548 |
Trypanosoma brucei | hexokinase, putative | 0.0079 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0079 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.0079 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0079 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.0079 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.0079 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.0079 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0079 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0022 | 0.0022 |
Leishmania major | hexokinase, putative | 0.0079 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.