Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | integrin alpha-ps | 0.0189 | 0.0559 | 0.0453 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0177 | 0.0477 | 0.0021 |
Brugia malayi | follicle stimulating hormone receptor | 0.024 | 0.0882 | 0.0771 |
Echinococcus granulosus | integrin beta 2 | 0.1231 | 0.7238 | 1 |
Brugia malayi | Integrin alpha cytoplasmic region family protein | 0.0614 | 0.328 | 0.3198 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.1251 | 0.7364 | 0.7332 |
Loa Loa (eye worm) | hypothetical protein | 0.0614 | 0.328 | 0.3198 |
Brugia malayi | Kelch motif family protein | 0.0253 | 0.0964 | 0.0854 |
Schistosoma mansoni | integrin beta subunit | 0.0979 | 0.5619 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.0463 | 0.0271 |
Echinococcus granulosus | integrin alpha ps | 0.0364 | 0.1677 | 0.1792 |
Echinococcus multilocularis | integrin alpha 3 | 0.0622 | 0.3333 | 0.4236 |
Schistosoma mansoni | integrin alpha-ps | 0.0364 | 0.1677 | 0.2562 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.0559 | 0.0444 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0253 | 0.0964 | 0.0854 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.0964 | 0.0854 |
Onchocerca volvulus | 0.0102 | 0 | 0.5 | |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0177 | 0.0477 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0637 | 0.3429 | 0.3349 |
Echinococcus multilocularis | integrin alpha ps | 0.0364 | 0.1677 | 0.1792 |
Echinococcus multilocularis | integrin beta 2 | 0.1231 | 0.7238 | 1 |
Loa Loa (eye worm) | integrin beta-2 | 0.1662 | 1 | 1 |
Schistosoma mansoni | integrin alpha | 0.0811 | 0.4547 | 0.7977 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0177 | 0.0477 | 0.0021 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.024 | 0.0882 | 0.0771 |
Echinococcus multilocularis | integrin alpha ps | 0.0364 | 0.1677 | 0.1792 |
Brugia malayi | hypothetical protein | 0.0253 | 0.0964 | 0.0854 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0463 | 0.0347 |
Echinococcus granulosus | integrin alpha 3 | 0.0622 | 0.3333 | 0.4236 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.2215 | 0.212 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0177 | 0.0477 | 0.0021 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.0811 | 0.4547 | 0.4481 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0177 | 0.0477 | 0.0361 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.