Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | stearoyl-CoA desaturase (delta-9-desaturase) | Starlite/ChEMBL | References |
Mus musculus | stearoyl-Coenzyme A desaturase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0223 | 1 | 1 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.0223 | 1 | 0.5 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.0205 | 0 | 0.5 |
Onchocerca volvulus | 0.0223 | 1 | 0.5 | |
Leishmania major | fatty-acid desaturase, putative | 0.0223 | 1 | 0.5 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0205 | 0 | 0.5 |
Brugia malayi | acyl-CoA desaturase | 0.0205 | 0 | 0.5 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0205 | 0 | 0.5 |
Onchocerca volvulus | 0.0223 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.