Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glycogen phosphorylase | 0.021 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.021 | 1 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.021 | 1 | 1 |
Giardia lamblia | Glycogen phosphorylase | 0.021 | 1 | 0.5 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0065 | 0 | 0.5 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0065 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0577 | 0.0475 |
Echinococcus multilocularis | glycogen phosphorylase | 0.021 | 1 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0065 | 0 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.021 | 1 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0091 | 0.1799 | 0.1799 |
Echinococcus granulosus | acetylcholinesterase | 0.0073 | 0.0577 | 0.0475 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.021 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0073 | 0.0577 | 0.0475 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0073 | 0.0577 | 0.0475 |
Schistosoma mansoni | glycogen phosphorylase | 0.0091 | 0.1799 | 0.171 |
Loa Loa (eye worm) | carboxylesterase | 0.0073 | 0.0577 | 0.0475 |
Schistosoma mansoni | glycogen phosphorylase | 0.021 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.021 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0091 | 0.1799 | 0.1799 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.021 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0073 | 0.0577 | 0.0475 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.021 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0073 | 0.0577 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0577 | 0.0475 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.021 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0577 | 0.0475 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0066 | 0.0107 | 0.0107 |
Schistosoma mansoni | glycogen phosphorylase | 0.021 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0073 | 0.0577 | 0.0475 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0577 | 0.0475 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0065 | 0 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.021 | 1 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0066 | 0.0107 | 0.0107 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.021 | 1 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0073 | 0.0577 | 0.0475 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0065 | 0 | 0.5 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0091 | 0.1799 | 0.5 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0091 | 0.1799 | 0.1799 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.021 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0073 | 0.0577 | 0.0475 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0091 | 0.1799 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.