Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | melanin-concentrating hormone receptor 1 | Starlite/ChEMBL | References |
Homo sapiens | potassium voltage-gated channel, subfamily H (eag-related), member 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.1878 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0013 | 0.0022 | 0.0022 |
Schistosoma mansoni | lysosomal Pro-Xaa carboxypeptidase (S28 family) | 0.1878 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Giardia lamblia | Thymus-specific serine protease precursor | 0.041 | 0.2146 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0022 | 0.0022 |
Brugia malayi | Serine protease Z688.6 precursor | 0.041 | 0.2146 | 0.2146 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.2146 | 0.2146 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0013 | 0.0022 | 0.0022 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0013 | 0.0022 | 0.0022 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Toxoplasma gondii | serine carboxypeptidase s28 protein | 0.041 | 0.2146 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0045 | 0.0191 | 0.0191 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.041 | 0.2146 | 1 |
Brugia malayi | Serine protease Z688.6 precursor | 0.041 | 0.2146 | 0.2146 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0045 | 0.0191 | 0.0191 |
Onchocerca volvulus | 0.041 | 0.2146 | 0.5 | |
Trypanosoma cruzi | putative prolyl carboxypeptidase, putative | 0.041 | 0.2146 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0013 | 0.0022 | 0.0022 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.041 | 0.2146 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase S28, putative | 0.041 | 0.2146 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.1878 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.041 | 0.2146 | 1 |
Trypanosoma cruzi | serine carboxypeptidase S28, putative | 0.041 | 0.2146 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1878 | 1 | 1 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.041 | 0.2146 | 0.2146 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.041 | 0.2146 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1878 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0013 | 0.0022 | 0.0022 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.0213 | 0.0213 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0013 | 0.0022 | 0.0022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.041 | 0.2146 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0175 | 0.0818 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.041 | 0.2146 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0175 | 0.0818 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0045 | 0.0191 | 0.0191 |
Trichomonas vaginalis | conserved hypothetical protein | 0.041 | 0.2146 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.041 | 0.2146 | 0.2146 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0045 | 0.0191 | 0.0191 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.041 | 0.2146 | 0.2146 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0013 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.016 | 0.016 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.0213 | 0.0213 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.041 | 0.2146 | 1 |
Giardia lamblia | Serine peptidase, putative | 0.041 | 0.2146 | 0.5 |
Trichomonas vaginalis | lysosomal pro-X carboxypeptidase, putative | 0.041 | 0.2146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1878 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.