Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.4055 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.4055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Echinococcus granulosus | cathepsin b | 0.4055 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.4055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Loa Loa (eye worm) | cathepsin B | 0.3576 | 0.8538 | 0.8473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Echinococcus granulosus | cathepsin b | 0.4055 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0914 | 0.0424 | 0.0424 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Leishmania major | cathepsin L-like protease | 0.1588 | 0.2479 | 0.1591 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1588 | 0.2479 | 0.2479 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Onchocerca volvulus | Cathepsin F homolog | 0.1212 | 0.1333 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.3576 | 0.8538 | 0.5 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0852 | 0.0238 | 0.0238 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.4055 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1588 | 0.2479 | 0.2479 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.4055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Echinococcus multilocularis | cathepsin b | 0.4055 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1212 | 0.1333 | 0.1333 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Brugia malayi | Cathepsin L-like precursor | 0.1212 | 0.1333 | 0.1333 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0914 | 0.0424 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Plasmodium vivax | vivapain-2 | 0.1212 | 0.1333 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1212 | 0.1333 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1212 | 0.1333 | 1 |
Leishmania major | cathepsin L-like protease | 0.1588 | 0.2479 | 0.1591 |
Echinococcus multilocularis | cathepsin b | 0.4055 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1212 | 0.1333 | 0.0949 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Onchocerca volvulus | Cathepsin L homolog | 0.1212 | 0.1333 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3576 | 0.8538 | 0.8538 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1212 | 0.1333 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0914 | 0.0424 | 0.0497 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1212 | 0.1333 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1212 | 0.1333 | 0.0949 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3576 | 0.8538 | 0.8538 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Brugia malayi | Cathepsin L-like precursor | 0.1212 | 0.1333 | 0.1333 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1212 | 0.1333 | 0.1333 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Echinococcus granulosus | cathepsin l1 | 0.0914 | 0.0424 | 0.0424 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1212 | 0.1333 | 0.1333 |
Loa Loa (eye worm) | fibroinase | 0.1212 | 0.1333 | 0.0949 |
Echinococcus multilocularis | cysteine protease | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0914 | 0.0424 | 0.0497 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1212 | 0.1333 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Giardia lamblia | Cathepsin B precursor | 0.3576 | 0.8538 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.129 | 0.157 | 0.157 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0914 | 0.0424 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.1333 | 0.0949 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Plasmodium vivax | vivapain-2 | 0.1212 | 0.1333 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Echinococcus granulosus | cathepsin l1 | 0.1212 | 0.1333 | 0.1333 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1212 | 0.1333 | 0.1333 |
Giardia lamblia | Cathepsin B precursor | 0.3576 | 0.8538 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Onchocerca volvulus | Cathepsin L homolog | 0.1212 | 0.1333 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1212 | 0.1333 | 0.0949 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Loa Loa (eye worm) | hypothetical protein | 0.4055 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Leishmania major | cathepsin L-like protease | 0.1588 | 0.2479 | 0.1591 |
Brugia malayi | Cathepsin L-like precursor | 0.1212 | 0.1333 | 0.1333 |
Toxoplasma gondii | cathepsin B | 0.3576 | 0.8538 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1212 | 0.1333 | 0.0949 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1588 | 0.2479 | 0.2903 |
Echinococcus multilocularis | cysteine protease | 0.1212 | 0.1333 | 0.1333 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1212 | 0.1333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0914 | 0.0424 | 0.0424 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Brugia malayi | Cathepsin L-like precursor | 0.1212 | 0.1333 | 0.1333 |
Brugia malayi | Cathepsin L-like precursor | 0.1212 | 0.1333 | 0.1333 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.3576 | 0.8538 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0914 | 0.0424 | 0.0424 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1212 | 0.1333 | 0.1561 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1588 | 0.2479 | 0.2479 |
Brugia malayi | cathepsin L-like precursor | 0.0914 | 0.0424 | 0.0424 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.3576 | 0.8538 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1212 | 0.1333 | 0.1333 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1212 | 0.1333 | 0.1333 |
Onchocerca volvulus | 0.1212 | 0.1333 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1588 | 0.2479 | 0.2479 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.3576 | 0.8538 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.