Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | tolloid-like 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0056 | 0.0135 | 0.0135 |
Echinococcus granulosus | Tolloid protein 1 | 0.0056 | 0.0135 | 0.0129 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.2945 | 1 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0018 | 0.0006 | 0.5 |
Brugia malayi | Fibulin-1 precursor | 0.0018 | 0.0006 | 0.0006 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0018 | 0.0006 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.2309 | 0.7827 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.118 | 0.3974 | 0.3974 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | AStacin protease | 0.0035 | 0.0064 | 0.0064 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0056 | 0.0135 | 0.0129 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.2309 | 0.7827 | 0.5 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.2945 | 1 | 1 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.2945 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2309 | 0.7827 | 0.7827 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.2309 | 0.7827 | 0.5 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.2945 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0127 | 0.0127 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0018 | 0.0006 | 0.0006 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0056 | 0.0135 | 0.0135 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.2309 | 0.7827 | 0.7827 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0006 | 0.0006 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.2945 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0018 | 0.0006 | 0.0006 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.