Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hypothetical protein | 0.002 | 0.0029 | 0.0226 |
Schistosoma mansoni | plexin | 0.0028 | 0.0302 | 0.3035 |
Brugia malayi | Plexin repeat family protein | 0.0047 | 0.0996 | 0.0996 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0029 | 0.0295 |
Echinococcus granulosus | semaphorin 1A | 0.002 | 0.0029 | 0.0226 |
Echinococcus granulosus | semaphorin 5B | 0.002 | 0.0029 | 0.0226 |
Echinococcus granulosus | plexin a4 | 0.0056 | 0.13 | 1 |
Echinococcus multilocularis | semaphorin 5B | 0.002 | 0.0029 | 0.0226 |
Toxoplasma gondii | hypothetical protein | 0.0246 | 0.7953 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0029 | 0.0295 |
Brugia malayi | hypothetical protein | 0.002 | 0.0029 | 0.0029 |
Brugia malayi | hypothetical protein | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.7953 | 0.7947 |
Schistosoma mansoni | semaphorin 5-related | 0.002 | 0.0029 | 0.0295 |
Onchocerca volvulus | 0.0047 | 0.0996 | 1 | |
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.0246 | 0.7953 | 0.7947 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.7953 | 0.7947 |
Loa Loa (eye worm) | plexin A | 0.0056 | 0.13 | 0.1274 |
Brugia malayi | plexin A | 0.0056 | 0.13 | 0.13 |
Brugia malayi | Sema domain containing protein | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.7953 | 0.7947 |
Brugia malayi | Sema domain containing protein | 0.002 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0302 | 0.0274 |
Schistosoma mansoni | plexin | 0.0047 | 0.0996 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0996 | 0.0969 |
Echinococcus multilocularis | plexin a4 | 0.0056 | 0.13 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0302 | 0.3035 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.