Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0079 | 0 | 0.5 |
Trypanosoma brucei | squalene monooxygenase, putative | 0.0242 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0163 | 0.5123 | 1 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0242 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.5123 | 1 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0242 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potentiation (functional) | = 0 % | % potentiation of responses mediated by 100 microM L-glutamate in human transfected HEK293 cells expressing homomeric iGluR4 flip receptors at a dose of 3 uM. | ChEMBL. | 11985477 |
Potentiation (functional) | = 0 % | % potentiation of responses mediated by 100 microM L-glutamate in human transfected HEK293 cells expressing homomeric iGluR4 flip receptors at a dose of 3 uM. | ChEMBL. | 11985477 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.