Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.5034 | 1 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0018 | 0.3986 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.5034 | 0.5034 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.5034 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.5034 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.5034 | 0.5034 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.5034 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.5034 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.5034 | 1 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0018 | 0.3986 | 0.5 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.5034 | 0.5034 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.5034 | 0.3387 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0018 | 0.3986 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.5034 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.5034 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.5034 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.5034 | 0.3387 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.5034 | 0.5034 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.5034 | 0.5034 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.5034 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.5034 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.5034 | 0.5034 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.