Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.8786 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.4216 | 0.4216 |
Onchocerca volvulus | 0.0031 | 0.4216 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.8786 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.4216 | 0.4216 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.8786 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.4216 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.4216 | 0.4216 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.4216 | 0.4216 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.8786 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.4216 | 0.4216 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.4216 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.4216 | 0.4216 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.8786 | 0.8786 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.8786 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.4216 | 0.4798 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.4216 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.4216 | 0.4216 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.8786 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.4216 | 0.4798 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.8786 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.4216 | 0.4798 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.4216 | 0.4216 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.5342 | 0.5342 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.4216 | 0.4798 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.4216 | 0.4216 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.4216 | 0.4798 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.4216 | 0.4798 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5342 | 0.608 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.4216 | 0.4216 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.8786 | 0.8786 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.4216 | 0.4216 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.4216 | 0.4798 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.4216 | 0.4798 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.4216 | 0.4216 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.4216 | 0.4798 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.4216 | 0.4798 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.4216 | 0.4216 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.5342 | 0.5342 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4216 | 0.4216 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.4216 | 0.4798 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.