Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Echinococcus granulosus | integrin alpha ps | 0.0834 | 0.2011 | 0.4323 |
Echinococcus multilocularis | integrin alpha 3 | 0.1425 | 0.4337 | 1 |
Schistosoma mansoni | hypothetical protein | 0.04 | 0.0305 | 0.0113 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0322 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0434 | 0.044 | 0.014 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1026 | 0.2766 | 0.2539 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Echinococcus granulosus | integrin alpha ps | 0.04 | 0.0305 | 0.016 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Echinococcus multilocularis | integrin alpha ps | 0.0834 | 0.2011 | 0.4323 |
Echinococcus multilocularis | integrin alpha ps | 0.04 | 0.0305 | 0.016 |
Echinococcus multilocularis | integrin alpha ps | 0.0834 | 0.2011 | 0.4323 |
Loa Loa (eye worm) | hypothetical protein | 0.1406 | 0.4262 | 0.4082 |
Schistosoma mansoni | integrin alpha-ps | 0.0434 | 0.044 | 0.0346 |
Schistosoma mansoni | integrin alpha | 0.1859 | 0.6043 | 1 |
Schistosoma mansoni | integrin alpha-ps | 0.0834 | 0.2011 | 0.3052 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.1859 | 0.6043 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.146 | 0.4472 | 0.4298 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0322 | 0 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0322 | 0 | 0.5 |
Echinococcus granulosus | integrin alpha 3 | 0.1425 | 0.4337 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 26.9 mM | Inhibitory activity against Arabinose-5-phosphate isomerase | ChEMBL. | 6429331 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.