Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | protein kinase C, delta | Starlite/ChEMBL | References |
Homo sapiens | protein kinase C, theta | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Onchocerca volvulus | Get druggable targets OG5_132502 | All targets in OG5_132502 | |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Toxoplasma gondii | AGC kinase | 0.0026 | 0.0017 | 0.5 |
Brugia malayi | protein kinase C II. | 0.0044 | 0.0563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.9227 | 0.9226 |
Entamoeba histolytica | protein kinase, putative | 0.0026 | 0.0017 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0026 | 0.0017 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.9227 | 0.9226 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.9774 | 0.9773 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.9227 | 0.9226 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0044 | 0.0563 | 0.0547 |
Onchocerca volvulus | 0.0333 | 0.9227 | 0.5 | |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0044 | 0.0563 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0563 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0563 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0044 | 0.0563 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0.0563 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0026 | 0.0017 | 0.5 |
Schistosoma mansoni | atypical protein kinase C | 0.0044 | 0.0563 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0044 | 0.0563 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0026 | 0.0017 | 0.5 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0044 | 0.0563 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0026 | 0.0017 | 0.5 |
Echinococcus multilocularis | protein kinase c iota type | 0.0044 | 0.0563 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0044 | 0.0563 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0026 | 0.0017 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.