Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0202 | 0.0202 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 1 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.5917 | 0.5568 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 1 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.5917 | 0.5833 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.8415 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 1 | 0.5 |
Onchocerca volvulus | 0.0031 | 0.5917 | 0.5 | |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 1 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 1 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 1 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.5917 | 0.5568 |
Onchocerca volvulus | 0.0031 | 0.5917 | 0.5 | |
Echinococcus granulosus | lamin | 0.0031 | 0.5917 | 0.5833 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 1 | 0.5 |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 1 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 1 | 0.5 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.8415 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.5917 | 0.5917 |
Echinococcus multilocularis | lamin | 0.0031 | 0.5917 | 0.5833 |
Echinococcus multilocularis | musashi | 0.0031 | 0.5917 | 0.5833 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0789 | 0.0789 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0042 | 1 | 0.5 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.5917 | 0.5917 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.5917 | 0.5833 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.5917 | 0.5917 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 1 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 1 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.5917 | 0.5833 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.5715 | 0.5715 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.