Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.018 | 0.1334 | 1 |
Brugia malayi | serine/threonine kinase 12 | 0.018 | 0.1334 | 0.1334 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Toxoplasma gondii | aurora kinase | 0.018 | 0.1334 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.018 | 0.1334 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.018 | 0.1334 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0166 | 0.0166 |
Entamoeba histolytica | protein kinase , putative | 0.018 | 0.1334 | 0.5 |
Leishmania major | protein kinase, putative | 0.018 | 0.1334 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.018 | 0.1334 | 0.1334 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0396 | 0.3628 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Giardia lamblia | Kinase, TTK | 0.0396 | 0.3628 | 1 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0396 | 0.3628 | 1 |
Trypanosoma brucei | aurora B kinase | 0.018 | 0.1334 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.018 | 0.1334 | 0.1334 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0396 | 0.3628 | 1 |
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0396 | 0.3628 | 1 |
Brugia malayi | serine/threonine protein kinase 6 | 0.018 | 0.1334 | 0.1334 |
Loa Loa (eye worm) | TTK protein kinase | 0.0396 | 0.3628 | 0.3628 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.018 | 0.1334 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0997 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0054 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.018 | 0.1334 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.018 | 0.1334 | 0.1334 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0396 | 0.3628 | 1 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.018 | 0.1334 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0396 | 0.3628 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.018 | 0.1334 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.018 | 0.1334 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0396 | 0.3628 | 0.3628 |
Trypanosoma cruzi | aurora B kinase, putative | 0.018 | 0.1334 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.018 | 0.1334 | 0.1334 |
Trichomonas vaginalis | AGC family protein kinase | 0.018 | 0.1334 | 0.3375 |
Brugia malayi | hypothetical protein | 0.007 | 0.0166 | 0.0166 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.