Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | transient receptor potential channel | 0.0065 | 0.3252 | 0.0957 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.2849 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0099 | 0.7055 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0065 | 0.3252 | 0.4609 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0095 | 0.668 | 0.9469 |
Onchocerca volvulus | Huntingtin homolog | 0.0124 | 1 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.2849 | 0.4039 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.2849 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 1 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0065 | 0.3252 | 0.4609 |
Onchocerca volvulus | Huntingtin homolog | 0.0124 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.7055 | 0.7055 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0095 | 0.668 | 0.9469 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.2849 | 0.5 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0099 | 0.7055 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.2849 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.2849 | 0.5 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0099 | 0.7055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 1 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0065 | 0.3252 | 0.4609 |
Schistosoma mansoni | transient receptor potential channel | 0.0065 | 0.3252 | 0.0957 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0065 | 0.3252 | 0.4609 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.2877 | 0.2877 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.2849 | 0.4039 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.2849 | 0.5 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0099 | 0.7055 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | >= 256 nmol/ml | Antimicrobial activity against Escherichia coli | ChEMBL. | 19874036 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.