Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | transcription factor LCR-F1 | 0.0034 | 0.7205 | 0.6547 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0018 | 0.1904 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Leishmania major | DNA polymerase eta, putative | 0.0043 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.003 | 0.577 | 0.4775 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Echinococcus granulosus | dna polymerase eta | 0.0043 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.7205 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0043 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0018 | 0.1904 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0018 | 0.1904 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0043 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0043 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0034 | 0.7205 | 0.6547 |
Giardia lamblia | DINP protein human, muc B family | 0.0018 | 0.1904 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.7205 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0018 | 0.1904 | 0.1904 |
Trypanosoma brucei | unspecified product | 0.0018 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0018 | 0.1904 | 0.1904 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0034 | 0.7205 | 0.6547 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.7205 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Brugia malayi | hypothetical protein | 0.0034 | 0.7205 | 0.6547 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0018 | 0.1904 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0018 | 0.1904 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 1 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.003 | 0.577 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0018 | 0.1904 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0018 | 0.1904 | 0.1904 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.003 | 0.577 | 0.4775 |
Echinococcus multilocularis | dna polymerase eta | 0.0043 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.7205 | 0.6547 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.7205 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.1904 | 0.1904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.