Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | ferritin, putative | 0.0008 | 0 | 0.5 |
Entamoeba histolytica | kinesin, putative | 0.0032 | 0.0995 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1518 | 1 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0008 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1518 | 0.1518 |
Schistosoma mansoni | kinesin eg-5 | 0.0032 | 0.0995 | 0.1149 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1518 | 1 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0008 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1518 | 0.1518 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0008 | 0 | 0.5 |
Plasmodium vivax | kinesin-5 | 0.0032 | 0.0995 | 0.5 |
Echinococcus multilocularis | kinesin family 1 | 0.0247 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1518 | 0.1518 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1518 | 0.1518 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1518 | 0.1753 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0.8655 | 1 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0032 | 0.0995 | 0.5 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0008 | 0 | 0.5 |
Giardia lamblia | Kinesin-5 | 0.0032 | 0.0995 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1518 | 0.1753 |
Plasmodium falciparum | kinesin-5 | 0.0032 | 0.0995 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1518 | 0.1753 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.