Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | geminin | 0.0177 | 0.6747 | 1 |
Onchocerca volvulus | 0.0102 | 0.2789 | 0.5 | |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0176 | 0.674 | 0.999 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0176 | 0.674 | 0.999 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.6747 | 0.6747 |
Schistosoma mansoni | peptidylglycine monooxygenase | 0.0126 | 0.404 | 0.404 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0126 | 0.404 | 0.5995 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0176 | 0.674 | 1 |
Echinococcus granulosus | peptidyl glycine alpha amidating monooxygenase | 0.0126 | 0.404 | 0.5988 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.404 | 0.5995 |
Schistosoma mansoni | alpha-glucosidase | 0.0152 | 0.5435 | 0.5435 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0128 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0128 | 0.019 |
Echinococcus multilocularis | peptidyl glycine alpha amidating monooxygenase | 0.0126 | 0.404 | 0.5988 |
Schistosoma mansoni | alpha-glucosidase | 0.0152 | 0.5435 | 0.5435 |
Schistosoma mansoni | peptidyl-glycine monooxygenase | 0.0126 | 0.404 | 0.404 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0176 | 0.674 | 1 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0126 | 0.404 | 0.5995 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0176 | 0.674 | 0.999 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0128 | 0.019 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0128 | 0.019 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.6747 | 0.6747 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein | 0.0064 | 0.0754 | 0.1119 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0062 | 0.0655 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.404 | 0.5995 |
Echinococcus granulosus | geminin | 0.0177 | 0.6747 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.