Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.0405 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0183 | 0.2654 | 0.2654 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1777 | 0.1777 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0183 | 0.2654 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0072 | 0.0405 | 0.0405 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0182 | 0.2625 | 0.2625 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0072 | 0.0405 | 0.0405 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0183 | 0.2654 | 0.2654 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0544 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.0405 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0183 | 0.2654 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1339 | 0.1339 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0544 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0072 | 0.0405 | 0.0405 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0183 | 0.2654 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0544 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.028 | 0.4628 | 0.4628 |
Brugia malayi | hypothetical protein | 0.014 | 0.1777 | 0.1777 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0183 | 0.2654 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0544 | 1 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0072 | 0.0405 | 0.0405 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.0405 | 0.5 |
Brugia malayi | hypothetical protein | 0.0118 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0544 | 1 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0183 | 0.2654 | 0.2654 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0072 | 0.0405 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0183 | 0.2654 | 0.2654 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0183 | 0.2654 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0182 | 0.2625 | 0.2625 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0183 | 0.2654 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.